Cargando…

Impact of Liposomal Spherical Nucleic Acid Structure on Immunotherapeutic Function

[Image: see text] Liposomal spherical nucleic acids (L-SNAs) show significant promise as cancer immunotherapeutics. L-SNAs are highly modular nanoscale assemblies defined by a dense, upright radial arrangement of oligonucleotides around a liposomal core. Herein, we establish a set of L-SNA design ru...

Descripción completa

Detalles Bibliográficos
Autores principales:	Callmann, Cassandra E., Kusmierz, Caroline D., Dittmar, Jasper W., Broger, Leah, Mirkin, Chad A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161491/ https://www.ncbi.nlm.nih.gov/pubmed/34079904 http://dx.doi.org/10.1021/acscentsci.1c00181

Ejemplares similares

Defining the Design Parameters for in Vivo Enzyme Delivery Through Protein Spherical Nucleic Acids
por: Kusmierz, Caroline D., et al.
Publicado: (2020)

Liposomal Spherical Nucleic Acids
por: Banga, Resham J., et al.
Publicado: (2014)

Disrupting the Interplay between Programmed Cell Death Protein 1 and Programmed Death Ligand 1 with Spherical Nucleic Acids in Treating Cancer
por: Chou, Liyushang, et al.
Publicado: (2022)

Spherical nucleic acids as an infectious disease vaccine platform
por: Teplensky, Michelle H., et al.
Publicado: (2022)

Spherical nucleic acids for precision medicine
por: Mirkin, Chad A., et al.
Publicado: (2013)

Chemically Tuning the Antigen Release Kinetics from Spherical Nucleic Acids Maximizes Immune Stimulation
por: Skakuj, Kacper, et al.
Publicado: (2021)

Spherical Nucleic Acids with Tailored and Active Protein Coronae
por: Zhang, Wuliang, et al.
Publicado: (2019)

Intracellular Fate of Spherical Nucleic Acid Nanoparticle Conjugates
por: Wu, Xiaochen A., et al.
Publicado: (2014)

Design Considerations for RNA Spherical Nucleic Acids (SNAs)
por: Barnaby, Stacey N., et al.
Publicado: (2016)

Development of Spherical Nucleic Acids for Prostate Cancer Immunotherapy
por: Qin, Lei, et al.
Publicado: (2020)

Cross-Linked Micellar Spherical Nucleic Acids from Thermoresponsive Templates
por: Banga, Resham J., et al.
Publicado: (2017)

Defining the Structure of a Protein–Spherical Nucleic Acid Conjugate and Its Counterionic Cloud
por: Krishnamoorthy, Kurinji, et al.
Publicado: (2018)

Spherical Nucleic Acids as a Divergent Platform for Synthesizing RNA–Nanoparticle Conjugates through Enzymatic Ligation
por: Rouge, Jessica L., et al.
Publicado: (2014)

Relationships between Poly(ethylene glycol) Modifications on RNA–Spherical Nucleic Acid Conjugates and Cellular Uptake and Circulation Time
por: Chinen, Alyssa B., et al.
Publicado: (2016)

Doxorubicin and CpG loaded liposomal spherical nucleic acid for enhanced Cancer treatment
por: Deng, Bo, et al.
Publicado: (2022)

Nucleic acid-based supramolecular structures: vesicular spherical nucleic acids from a non-phospholipid nucleolipid
por: Dimitrov, Erik, et al.
Publicado: (2022)

Precision spherical nucleic acids for delivery of anticancer drugs
por: Bousmail, Danny, et al.
Publicado: (2017)

Assembly of Bleomycin Saccharide-Decorated Spherical Nucleic Acids
por: Tähtinen, Ville, et al.
Publicado: (2022)

Spherical nucleic acids: Organized nucleotide aggregates as versatile nanomedicine
por: Song, Yangmeihui, et al.
Publicado: (2022)

Rational Vaccinology: Harnessing Nanoscale Chemical Design for Cancer Immunotherapy
por: Huang, Ziyin, et al.
Publicado: (2022)

Spherical nucleic acid targeting microRNA-99b enhances intestinal MFG-E8 gene expression and restores enterocyte migration in lipopolysaccharide-induced septic mice
por: Wang, Xiao, et al.
Publicado: (2016)

Gene Regulation Using Spherical Nucleic Acids to Treat Skin Disorders
por: Holmes, Thomas R., et al.
Publicado: (2020)

Plaque‐Targeted Rapamycin Spherical Nucleic Acids for Synergistic Atherosclerosis Treatment
por: Guo, Yuanyuan, et al.
Publicado: (2022)

Original Synthesis of a Nucleolipid for Preparation of Vesicular Spherical Nucleic Acids
por: Dimitrov, Erik, et al.
Publicado: (2022)

Nanoarchitectonics of Spherical Nucleic Acids with Biodegradable Polymer Cores: Synthesis and Evaluation
por: Kalinova, Radostina, et al.
Publicado: (2022)

Spherical nucleic acids-based nanoplatforms for tumor precision medicine and immunotherapy
por: Liu, Songbin, et al.
Publicado: (2023)

Preparation of Surface-Supported Polylactide Spherical-Cap Particles
por: Kuśmierz, Barbara, et al.
Publicado: (2022)

Recent Advance of Liposome Nanoparticles for Nucleic Acid Therapy
por: Gao, Yongguang, et al.
Publicado: (2023)

Controlled Monofunctionalization of Molecular Spherical Nucleic Acids on a Buckminster Fullerene Core
por: Gulumkar, Vijay, et al.
Publicado: (2021)

Spherical Nucleic Acids as Precision Therapeutics for the Treatment of Cancer—From Bench to Bedside
por: Mahajan, Akanksha S., et al.
Publicado: (2022)

Tumor microenvironment-responsive spherical nucleic acid nanoparticles for enhanced chemo-immunotherapy
por: Ma, Bing, et al.
Publicado: (2023)

Cationic Liposomes as Vectors for Nucleic Acid and Hydrophobic Drug Therapeutics
por: Ewert, Kai K., et al.
Publicado: (2021)

Spherical Nucleic Acid Architecture Can Improve the Efficacy of Polycation-Mediated siRNA Delivery
por: Melamed, Jilian R., et al.
Publicado: (2018)

Design and enhanced gene silencing activity of spherical 2′-fluoroarabinose nucleic acids (FANA-SNAs)
por: Fakih, Hassan H., et al.
Publicado: (2021)

In Vivo Imaging of [60]Fullerene-Based Molecular Spherical Nucleic Acids by Positron Emission Tomography
por: Äärelä, Antti, et al.
Publicado: (2023)

Immunotherapeutic effect of BCG-polysaccharide nucleic acid powder on Mycobacterium tuberculosis-infected mice using microneedle patches
por: Yan, Qinying, et al.
Publicado: (2017)

Molecularly pure miktoarm spherical nucleic acids: preparation and usage as a scaffold for abiotic intracellular catalysis
por: Zhang, Bohan, et al.
Publicado: (2021)

Development of Theranostic Cationic Liposomes Designed for Image-Guided Delivery of Nucleic Acid
por: Do, Hai Doan, et al.
Publicado: (2020)

Complex Size and Surface Charge Determine Nucleic Acid Transfer by Fusogenic Liposomes
por: Hoffmann, Marco, et al.
Publicado: (2020)

Liposome Delivery of Nucleic Acids in Bacteria: Toward In Vivo Labeling of Human Microbiota
por: Moreira, Luís, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_bcg1g4d1aur5anr2b1cgft925i