The Timing and Abundance of IL-2Rβ (CD122) Expression Control Thymic iNKT Cell Generation and NKT1 Subset Differentiation

Invariant NKT (iNKT) cells are thymus-generated innate-like T cells, comprised of three distinct subsets with divergent effector functions. The molecular mechanism that drives the lineage trifurcation of immature iNKT cells into the NKT1, NKT2, and NKT17 subsets remains a controversial issue that re...

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Detalles Bibliográficos
Autores principales: Won, Hee Yeun, Kim, Hye Kyung, Crossman, Assiatu, Awasthi, Parirokh, Gress, Ronald E., Park, Jung-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161506/
https://www.ncbi.nlm.nih.gov/pubmed/34054809
http://dx.doi.org/10.3389/fimmu.2021.642856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161506/
https://www.ncbi.nlm.nih.gov/pubmed/34054809
http://dx.doi.org/10.3389/fimmu.2021.642856

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