Post-GWAS functional studies reveal an RA-associated CD40-induced NF-kB signal transduction and transcriptional regulation network targeted by class II HDAC inhibitors

Currently, it remains difficult to identify which single nucleotide polymorphisms (SNPs) identified by genome-wide association studies (GWAS) are functional and how various functional SNPs (fSNPs) interact and contribute to disease susceptibility. GWAS have identified a CD40 locus that is associated...

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Detalles Bibliográficos
Autores principales: Zou, Meijuan, Jiang, Danli, Wu, Ting, Zhang, Xiaoyu, Zhao, Yihan, Wu, Di, Sun, Wei, Cui, Jing, Moreland, Larry, Li, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Association Studies Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161515/
https://www.ncbi.nlm.nih.gov/pubmed/33517445
http://dx.doi.org/10.1093/hmg/ddab032

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