Exome sequencing revealed PDE11A as a novel candidate gene for early-onset Alzheimer’s disease

To identify novel risk genes and better understand the molecular pathway underlying Alzheimer’s disease (AD), whole-exome sequencing was performed in 215 early-onset AD (EOAD) patients and 255 unrelated healthy controls of Han Chinese ethnicity. Subsequent validation, computational annotation and in...

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Detalles Bibliográficos
Autores principales: Qin, Wei, Zhou, Aihong, Zuo, Xiumei, Jia, Longfei, Li, Fangyu, Wang, Qi, Li, Ying, Wei, Yiping, Jin, Hongmei, Cruchaga, Carlos, Benitez, Bruno A, Jia, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
General Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161517/
https://www.ncbi.nlm.nih.gov/pubmed/33835157
http://dx.doi.org/10.1093/hmg/ddab090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161517/
https://www.ncbi.nlm.nih.gov/pubmed/33835157
http://dx.doi.org/10.1093/hmg/ddab090

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