Limb-clasping, cognitive deficit and increased vulnerability to kainic acid-induced seizures in neuronal glycosylphosphatidylinositol deficiency mouse models

Posttranslational modification of a protein with glycosylphosphatidylinositol (GPI) is a conserved mechanism exists in all eukaryotes. Thus far, >150 human GPI-anchored proteins have been discovered and ~30 enzymes have been reported to be involved in the biosynthesis and maturation of mammalian...

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Detalles Bibliográficos
Autores principales: Kandasamy, Lenin C, Tsukamoto, Mina, Banov, Vitaliy, Tsetsegee, Sambuu, Nagasawa, Yutaro, Kato, Mitsuhiro, Matsumoto, Naomichi, Takeda, Junji, Itohara, Shigeyoshi, Ogawa, Sonoko, Young, Larry J, Zhang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
General Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161520/
https://www.ncbi.nlm.nih.gov/pubmed/33607654
http://dx.doi.org/10.1093/hmg/ddab052

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