Cargando…
Peptide late-stage C(sp(3))–H arylation by native asparagine assistance without exogenous directing groups
There is a strong demand for novel native peptide motifs for post-synthetic modifications of peptides without pre-installation and subsequent removal of directing groups. Herein, we report an efficient method for peptide late-stage C(sp(3))–H arylations assisted by the unmodified side chain of aspar...
Autores principales: | Weng, Yiyi, Ding, Xingxing, Oliveira, João C. A., Xu, Xiaobin, Kaplaneris, Nikolaos, Zhu, Meijie, Chen, Hantao, Chen, Zhuo, Ackermann, Lutz |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161531/ https://www.ncbi.nlm.nih.gov/pubmed/34094199 http://dx.doi.org/10.1039/d0sc03830j |
Ejemplares similares
-
Late-stage C(sp(2))–H and C(sp(3))–H glycosylation of C-aryl/alkyl glycopeptides: mechanistic insights and fluorescence labeling
por: Wu, Jun, et al.
Publicado: (2020) -
Remote C−H Glycosylation by Ruthenium(II) Catalysis: Modular Assembly of meta‐C‐Aryl Glycosides
por: Wu, Jun, et al.
Publicado: (2022) -
Earth-abundant 3d transition metals on the rise in catalysis
por: Kaplaneris, Nikolaos, et al.
Publicado: (2022) -
Electrochemical
Late-Stage Functionalization
por: Wang, Yulei, et al.
Publicado: (2023) -
Late-stage peptide C–H alkylation for bioorthogonal C–H activation featuring solid phase peptide synthesis
por: Schischko, Alexandra, et al.
Publicado: (2019)