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Discovery and biosynthesis of bosamycins from Streptomyces sp. 120454

Nonribosomal peptides (NRPs) that are synthesized by modular megaenzymes known as nonribosomal peptide synthetases (NRPSs) are a rich source for drug discovery. By targeting an unusual NRPS architecture, we discovered an unusual biosynthetic gene cluster (bsm) from Streptomyces sp. 120454 and identi...

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Detalles Bibliográficos
Autores principales:	Xu, Zi Fei, Bo, Sheng Tao, Wang, Mei Jing, Shi, Jing, Jiao, Rui Hua, Sun, Yang, Xu, Qiang, Tan, Ren Xiang, Ge, Hui Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161544/ https://www.ncbi.nlm.nih.gov/pubmed/34094195 http://dx.doi.org/10.1039/d0sc03469j

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