LncRNA DNM3OS regulates GREM2 via miR-127-5p to suppress early chondrogenic differentiation of rat mesenchymal stem cells under hypoxic conditions

BACKGROUND: Improved chondrogenic differentiation of mesenchymal stem cells (MSCs) by genetic regulation is a potential method for regenerating articular cartilage. MiR-127-5p has been reported to promote cartilage differentiation of rat bone marrow MSCs (rMSCs); however, the regulatory mechanisms u...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaozhong, Xu, Wangyang, Wang, Yeyang, Zhang, Hui, Zhang, Li, Li, Chao, Yao, Shun, Huang, Zixiang, Huang, Lishan, Luo, Dixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161583/
https://www.ncbi.nlm.nih.gov/pubmed/34049478
http://dx.doi.org/10.1186/s11658-021-00269-6

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