The polyphenol/saponin-rich Rhus tripartita extract has an apoptotic effect on THP-1 cells through the PI3K/AKT/mTOR signaling pathway

BACKGROUND: Hyperactivation of mechanistic target of rapamycin (mTOR) signaling pathway is involved in the regulation of cellular growth, proliferation, and more in general, is a common phenomenon in most types of cancers. Thus, natural substances targeting this pathway can be of great therapeutic p...

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Detalles Bibliográficos
Autores principales: Tlili, Hajer, Macovei, Anca, Buonocore, Daniela, Lanzafame, Manuela, Najjaa, Hanen, Lombardi, Anita, Pagano, Andrea, Dossena, Maurizia, Verri, Manuela, Arfa, Abdelkarim Ben, Neffati, Mohamed, Doria, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161611/
https://www.ncbi.nlm.nih.gov/pubmed/34044827
http://dx.doi.org/10.1186/s12906-021-03328-9

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