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Chimeric HP-PRRSV2 containing an ORF2-6 consensus sequence induces antibodies with broadly neutralizing activity and confers cross protection against virulent NADC30-like isolate

Due to the substantial genetic diversity of porcine reproductive and respiratory syndrome virus (PRRSV), commercial PRRS vaccines fail to provide sufficient cross protection. Previous studies have confirmed the existence of PRRSV broadly neutralizing antibodies (bnAbs). However, bnAbs are rarely ind...

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Detalles Bibliográficos
Autores principales:	Chen, Nanhua, Li, Shubin, Tian, Yunfei, Li, Xinshuai, Li, Shuai, Li, Jixiang, Qiu, Ming, Sun, Zhe, Xiao, Yanzhao, Yan, Xilin, Lin, Hong, Yu, Xiuling, Tian, Kegong, Shang, Shaobin, Zhu, Jianzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161975/ https://www.ncbi.nlm.nih.gov/pubmed/34044890 http://dx.doi.org/10.1186/s13567-021-00944-8

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