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A FRET-based fluorescent Zn(2+) sensor: 3D ratiometric imaging, flow cytometric tracking and cisplatin-induced Zn(2+) fluctuation monitoring
Monitoring labile Zn(2+) homeostasis is of great importance for the study of physiological functions of Zn(2+) in biological systems. Here we report a novel ratiometric fluorescent Zn(2+) sensor, CPBT, which was constructed based on chelation-induced alteration of FRET efficiency. CPBT was readily c...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162301/ https://www.ncbi.nlm.nih.gov/pubmed/34123194 http://dx.doi.org/10.1039/d0sc03037f |