A FRET-based fluorescent Zn(2+) sensor: 3D ratiometric imaging, flow cytometric tracking and cisplatin-induced Zn(2+) fluctuation monitoring

Monitoring labile Zn(2+) homeostasis is of great importance for the study of physiological functions of Zn(2+) in biological systems. Here we report a novel ratiometric fluorescent Zn(2+) sensor, CPBT, which was constructed based on chelation-induced alteration of FRET efficiency. CPBT was readily c...

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Detalles Bibliográficos
Autores principales: Xu, Hongxia, Zhu, Chengcheng, Chen, Yuncong, Bai, Yang, Han, Zhong, Yao, Shankun, Jiao, Yang, Yuan, Hao, He, Weijiang, Guo, Zijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162301/
https://www.ncbi.nlm.nih.gov/pubmed/34123194
http://dx.doi.org/10.1039/d0sc03037f

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