Palladium-catalyzed hydroalkylation of methylenecyclopropanes with simple hydrazones

A palladium-catalyzed hydroalkylation reaction of methylenecyclopropanes via highly selective C–C σ-bond scission was achieved under mild conditions, in which simple hydrazones served as carbanion equivalents. This method featured good functional group compatibility, affording high yields of C-alkyl...

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Autores principales: Yao, Jinzhong, Chen, Zhangpei, Yu, Lin, Lv, Leiyang, Cao, Dawei, Li, Chao-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162302/
https://www.ncbi.nlm.nih.gov/pubmed/34094329
http://dx.doi.org/10.1039/d0sc01221a
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author Yao, Jinzhong
Chen, Zhangpei
Yu, Lin
Lv, Leiyang
Cao, Dawei
Li, Chao-Jun
author_facet Yao, Jinzhong
Chen, Zhangpei
Yu, Lin
Lv, Leiyang
Cao, Dawei
Li, Chao-Jun
author_sort Yao, Jinzhong
collection PubMed
description A palladium-catalyzed hydroalkylation reaction of methylenecyclopropanes via highly selective C–C σ-bond scission was achieved under mild conditions, in which simple hydrazones served as carbanion equivalents. This method featured good functional group compatibility, affording high yields of C-alkylated terminal alkenes.
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spelling pubmed-81623022021-06-04 Palladium-catalyzed hydroalkylation of methylenecyclopropanes with simple hydrazones Yao, Jinzhong Chen, Zhangpei Yu, Lin Lv, Leiyang Cao, Dawei Li, Chao-Jun Chem Sci Chemistry A palladium-catalyzed hydroalkylation reaction of methylenecyclopropanes via highly selective C–C σ-bond scission was achieved under mild conditions, in which simple hydrazones served as carbanion equivalents. This method featured good functional group compatibility, affording high yields of C-alkylated terminal alkenes. The Royal Society of Chemistry 2020-05-15 /pmc/articles/PMC8162302/ /pubmed/34094329 http://dx.doi.org/10.1039/d0sc01221a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Yao, Jinzhong
Chen, Zhangpei
Yu, Lin
Lv, Leiyang
Cao, Dawei
Li, Chao-Jun
Palladium-catalyzed hydroalkylation of methylenecyclopropanes with simple hydrazones
title Palladium-catalyzed hydroalkylation of methylenecyclopropanes with simple hydrazones
title_full Palladium-catalyzed hydroalkylation of methylenecyclopropanes with simple hydrazones
title_fullStr Palladium-catalyzed hydroalkylation of methylenecyclopropanes with simple hydrazones
title_full_unstemmed Palladium-catalyzed hydroalkylation of methylenecyclopropanes with simple hydrazones
title_short Palladium-catalyzed hydroalkylation of methylenecyclopropanes with simple hydrazones
title_sort palladium-catalyzed hydroalkylation of methylenecyclopropanes with simple hydrazones
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162302/
https://www.ncbi.nlm.nih.gov/pubmed/34094329
http://dx.doi.org/10.1039/d0sc01221a
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AT lvleiyang palladiumcatalyzedhydroalkylationofmethylenecyclopropaneswithsimplehydrazones
AT caodawei palladiumcatalyzedhydroalkylationofmethylenecyclopropaneswithsimplehydrazones
AT lichaojun palladiumcatalyzedhydroalkylationofmethylenecyclopropaneswithsimplehydrazones

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