Regioselective B(3,4)–H arylation of o-carboranes by weak amide coordination at room temperature

Palladium-catalyzed regioselective di- or mono-arylation of o-carboranes was achieved using weakly coordinating amides at room temperature. Therefore, a series of B(3,4)-diarylated and B(3)-monoarylated o-carboranes anchored with valuable functional groups were accessed for the first time. This stra...

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Autores principales: Liang, Yu-Feng, Yang, Long, Jei, Becky Bongsuiru, Kuniyil, Rositha, Ackermann, Lutz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162305/
https://www.ncbi.nlm.nih.gov/pubmed/34094330
http://dx.doi.org/10.1039/d0sc01515f
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author Liang, Yu-Feng
Yang, Long
Jei, Becky Bongsuiru
Kuniyil, Rositha
Ackermann, Lutz
author_facet Liang, Yu-Feng
Yang, Long
Jei, Becky Bongsuiru
Kuniyil, Rositha
Ackermann, Lutz
author_sort Liang, Yu-Feng
collection PubMed
description Palladium-catalyzed regioselective di- or mono-arylation of o-carboranes was achieved using weakly coordinating amides at room temperature. Therefore, a series of B(3,4)-diarylated and B(3)-monoarylated o-carboranes anchored with valuable functional groups were accessed for the first time. This strategy provided an efficient approach for the selective activation of B(3,4)–H bonds for regioselective functionalizations of o-carboranes.
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spelling pubmed-81623052021-06-04 Regioselective B(3,4)–H arylation of o-carboranes by weak amide coordination at room temperature Liang, Yu-Feng Yang, Long Jei, Becky Bongsuiru Kuniyil, Rositha Ackermann, Lutz Chem Sci Chemistry Palladium-catalyzed regioselective di- or mono-arylation of o-carboranes was achieved using weakly coordinating amides at room temperature. Therefore, a series of B(3,4)-diarylated and B(3)-monoarylated o-carboranes anchored with valuable functional groups were accessed for the first time. This strategy provided an efficient approach for the selective activation of B(3,4)–H bonds for regioselective functionalizations of o-carboranes. The Royal Society of Chemistry 2020-05-05 /pmc/articles/PMC8162305/ /pubmed/34094330 http://dx.doi.org/10.1039/d0sc01515f Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Liang, Yu-Feng
Yang, Long
Jei, Becky Bongsuiru
Kuniyil, Rositha
Ackermann, Lutz
Regioselective B(3,4)–H arylation of o-carboranes by weak amide coordination at room temperature
title Regioselective B(3,4)–H arylation of o-carboranes by weak amide coordination at room temperature
title_full Regioselective B(3,4)–H arylation of o-carboranes by weak amide coordination at room temperature
title_fullStr Regioselective B(3,4)–H arylation of o-carboranes by weak amide coordination at room temperature
title_full_unstemmed Regioselective B(3,4)–H arylation of o-carboranes by weak amide coordination at room temperature
title_short Regioselective B(3,4)–H arylation of o-carboranes by weak amide coordination at room temperature
title_sort regioselective b(3,4)–h arylation of o-carboranes by weak amide coordination at room temperature
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162305/
https://www.ncbi.nlm.nih.gov/pubmed/34094330
http://dx.doi.org/10.1039/d0sc01515f
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