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Total synthesis of biseokeaniamides A–C and late-stage electrochemically-enabled peptide analogue synthesis
The first total synthesis of cytotoxic cyanobacterial peptide natural products biseokeaniamides A–C is reported employing a robust solid-phase approach to peptide backbone construction followed by coupling of a key thiazole building block. To rapidly access natural product analogues, we have optimiz...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162360/ https://www.ncbi.nlm.nih.gov/pubmed/34094328 http://dx.doi.org/10.1039/d0sc03701j |