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Cytoplasmic MSH2 Related to Genomic Deletions in the MSH2/EPCAM Genes in Colorectal Cancer Patients With Suspected Lynch Syndrome
BACKGROUND: A large proportion of patients with Lynch syndrome (LS) have MSH2 abnormalities, but genotype-phenotype studies of MSH2 mutations in LS are still lacking. The aim of this study was to comprehensively analyze the clinicopathological characteristics and molecular basis of colorectal cancer...
Autores principales: | Dong, Lin, Zou, Shuangmei, Jin, Xianglan, Lu, Haizhen, Zhang, Ye, Guo, Lei, Cai, Jianqiang, Ying, Jianming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162378/ https://www.ncbi.nlm.nih.gov/pubmed/34055602 http://dx.doi.org/10.3389/fonc.2021.627460 |
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