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A Decade of Disparities in Diabetes Technology Use and HbA(1c) in Pediatric Type 1 Diabetes: A Transatlantic Comparison

OBJECTIVE: As diabetes technology use in youth increases worldwide, inequalities in access may exacerbate disparities in hemoglobin A(1c) (HbA(1c)). We hypothesized that an increasing gap in diabetes technology use by socioeconomic status (SES) would be associated with increased HbA(1c) disparities....

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Autores principales: Addala, Ananta, Auzanneau, Marie, Miller, Kellee, Maier, Werner, Foster, Nicole, Kapellen, Thomas, Walker, Ashby, Rosenbauer, Joachim, Maahs, David M., Holl, Reinhard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162452/
https://www.ncbi.nlm.nih.gov/pubmed/32938745
http://dx.doi.org/10.2337/dc20-0257
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author Addala, Ananta
Auzanneau, Marie
Miller, Kellee
Maier, Werner
Foster, Nicole
Kapellen, Thomas
Walker, Ashby
Rosenbauer, Joachim
Maahs, David M.
Holl, Reinhard W.
author_facet Addala, Ananta
Auzanneau, Marie
Miller, Kellee
Maier, Werner
Foster, Nicole
Kapellen, Thomas
Walker, Ashby
Rosenbauer, Joachim
Maahs, David M.
Holl, Reinhard W.
author_sort Addala, Ananta
collection PubMed
description OBJECTIVE: As diabetes technology use in youth increases worldwide, inequalities in access may exacerbate disparities in hemoglobin A(1c) (HbA(1c)). We hypothesized that an increasing gap in diabetes technology use by socioeconomic status (SES) would be associated with increased HbA(1c) disparities. RESEARCH DESIGN AND METHODS: Participants aged <18 years with diabetes duration ≥1 year in the Type 1 Diabetes Exchange (T1DX, U.S., n = 16,457) and Diabetes Prospective Follow-up (DPV, Germany, n = 39,836) registries were categorized into lowest (Q1) to highest (Q5) SES quintiles. Multiple regression analyses compared the relationship of SES quintiles with diabetes technology use and HbA(1c) from 2010–2012 to 2016–2018. RESULTS: HbA(1c) was higher in participants with lower SES (in 2010–2012 and 2016–2018, respectively: 8.0% and 7.8% in Q1 and 7.6% and 7.5% in Q5 for DPV; 9.0% and 9.3% in Q1 and 7.8% and 8.0% in Q5 for T1DX). For DPV, the association between SES and HbA(1c) did not change between the two time periods, whereas for T1DX, disparities in HbA(1c) by SES increased significantly (P < 0.001). After adjusting for technology use, results for DPV did not change, whereas the increase in T1DX was no longer significant. CONCLUSIONS: Although causal conclusions cannot be drawn, diabetes technology use is lowest and HbA(1c) is highest in those of the lowest SES quintile in the T1DX, and this difference for HbA(1c) broadened in the past decade. Associations of SES with technology use and HbA(1c) were weaker in the DPV registry.
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spelling pubmed-81624522022-01-01 A Decade of Disparities in Diabetes Technology Use and HbA(1c) in Pediatric Type 1 Diabetes: A Transatlantic Comparison Addala, Ananta Auzanneau, Marie Miller, Kellee Maier, Werner Foster, Nicole Kapellen, Thomas Walker, Ashby Rosenbauer, Joachim Maahs, David M. Holl, Reinhard W. Diabetes Care Emerging Technologies: Data Systems and Devices OBJECTIVE: As diabetes technology use in youth increases worldwide, inequalities in access may exacerbate disparities in hemoglobin A(1c) (HbA(1c)). We hypothesized that an increasing gap in diabetes technology use by socioeconomic status (SES) would be associated with increased HbA(1c) disparities. RESEARCH DESIGN AND METHODS: Participants aged <18 years with diabetes duration ≥1 year in the Type 1 Diabetes Exchange (T1DX, U.S., n = 16,457) and Diabetes Prospective Follow-up (DPV, Germany, n = 39,836) registries were categorized into lowest (Q1) to highest (Q5) SES quintiles. Multiple regression analyses compared the relationship of SES quintiles with diabetes technology use and HbA(1c) from 2010–2012 to 2016–2018. RESULTS: HbA(1c) was higher in participants with lower SES (in 2010–2012 and 2016–2018, respectively: 8.0% and 7.8% in Q1 and 7.6% and 7.5% in Q5 for DPV; 9.0% and 9.3% in Q1 and 7.8% and 8.0% in Q5 for T1DX). For DPV, the association between SES and HbA(1c) did not change between the two time periods, whereas for T1DX, disparities in HbA(1c) by SES increased significantly (P < 0.001). After adjusting for technology use, results for DPV did not change, whereas the increase in T1DX was no longer significant. CONCLUSIONS: Although causal conclusions cannot be drawn, diabetes technology use is lowest and HbA(1c) is highest in those of the lowest SES quintile in the T1DX, and this difference for HbA(1c) broadened in the past decade. Associations of SES with technology use and HbA(1c) were weaker in the DPV registry. American Diabetes Association 2021-01 2020-09-16 /pmc/articles/PMC8162452/ /pubmed/32938745 http://dx.doi.org/10.2337/dc20-0257 Text en © 2020 by the American Diabetes Association https://www.diabetesjournals.org/content/licenseReaders may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. More information is available at https://www.diabetesjournals.org/content/license.
spellingShingle Emerging Technologies: Data Systems and Devices
Addala, Ananta
Auzanneau, Marie
Miller, Kellee
Maier, Werner
Foster, Nicole
Kapellen, Thomas
Walker, Ashby
Rosenbauer, Joachim
Maahs, David M.
Holl, Reinhard W.
A Decade of Disparities in Diabetes Technology Use and HbA(1c) in Pediatric Type 1 Diabetes: A Transatlantic Comparison
title A Decade of Disparities in Diabetes Technology Use and HbA(1c) in Pediatric Type 1 Diabetes: A Transatlantic Comparison
title_full A Decade of Disparities in Diabetes Technology Use and HbA(1c) in Pediatric Type 1 Diabetes: A Transatlantic Comparison
title_fullStr A Decade of Disparities in Diabetes Technology Use and HbA(1c) in Pediatric Type 1 Diabetes: A Transatlantic Comparison
title_full_unstemmed A Decade of Disparities in Diabetes Technology Use and HbA(1c) in Pediatric Type 1 Diabetes: A Transatlantic Comparison
title_short A Decade of Disparities in Diabetes Technology Use and HbA(1c) in Pediatric Type 1 Diabetes: A Transatlantic Comparison
title_sort decade of disparities in diabetes technology use and hba(1c) in pediatric type 1 diabetes: a transatlantic comparison
topic Emerging Technologies: Data Systems and Devices
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162452/
https://www.ncbi.nlm.nih.gov/pubmed/32938745
http://dx.doi.org/10.2337/dc20-0257
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