Cargando…

Fulminant Guillain–Barré Syndrome Post Hemorrhagic Stroke: Two Case Reports

Guillain–Barré syndrome (GBS) is an acute, immune-mediated inflammatory peripheral polyneuropathy characterized by ascending paralysis. Most GBS cases follow gastrointestinal or chest infections. Some patients have been reported either following or concomitant with head trauma, neurosurgical procedu...

Descripción completa

Detalles Bibliográficos
Autores principales: Abdulmana, Sameeh, Al-Zahrani, Naif, Sharahely, Yahya, Bashir, Shahid, M. Al-Harbi, Talal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162529/
https://www.ncbi.nlm.nih.gov/pubmed/34066316
http://dx.doi.org/10.3390/neurolint13020019
_version_ 1783700733586046976
author Abdulmana, Sameeh
Al-Zahrani, Naif
Sharahely, Yahya
Bashir, Shahid
M. Al-Harbi, Talal
author_facet Abdulmana, Sameeh
Al-Zahrani, Naif
Sharahely, Yahya
Bashir, Shahid
M. Al-Harbi, Talal
author_sort Abdulmana, Sameeh
collection PubMed
description Guillain–Barré syndrome (GBS) is an acute, immune-mediated inflammatory peripheral polyneuropathy characterized by ascending paralysis. Most GBS cases follow gastrointestinal or chest infections. Some patients have been reported either following or concomitant with head trauma, neurosurgical procedures, and rarely hemorrhagic stroke. The exact pathogenesis is not entirely understood. However, blood–brain barrier damage may play an essential role in triggering the autoimmune activation that leads to post-stroke GBS. Here, we present two cases of fulminant GBS following hemorrhagic stroke to remind clinicians to be aware of this rare treatable complication if a stroke patient develops unexplainable flaccid paralysis with or without respiratory distress.
format Online
Article
Text
id pubmed-8162529
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-81625292021-05-29 Fulminant Guillain–Barré Syndrome Post Hemorrhagic Stroke: Two Case Reports Abdulmana, Sameeh Al-Zahrani, Naif Sharahely, Yahya Bashir, Shahid M. Al-Harbi, Talal Neurol Int Case Report Guillain–Barré syndrome (GBS) is an acute, immune-mediated inflammatory peripheral polyneuropathy characterized by ascending paralysis. Most GBS cases follow gastrointestinal or chest infections. Some patients have been reported either following or concomitant with head trauma, neurosurgical procedures, and rarely hemorrhagic stroke. The exact pathogenesis is not entirely understood. However, blood–brain barrier damage may play an essential role in triggering the autoimmune activation that leads to post-stroke GBS. Here, we present two cases of fulminant GBS following hemorrhagic stroke to remind clinicians to be aware of this rare treatable complication if a stroke patient develops unexplainable flaccid paralysis with or without respiratory distress. MDPI 2021-05-06 /pmc/articles/PMC8162529/ /pubmed/34066316 http://dx.doi.org/10.3390/neurolint13020019 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Abdulmana, Sameeh
Al-Zahrani, Naif
Sharahely, Yahya
Bashir, Shahid
M. Al-Harbi, Talal
Fulminant Guillain–Barré Syndrome Post Hemorrhagic Stroke: Two Case Reports
title Fulminant Guillain–Barré Syndrome Post Hemorrhagic Stroke: Two Case Reports
title_full Fulminant Guillain–Barré Syndrome Post Hemorrhagic Stroke: Two Case Reports
title_fullStr Fulminant Guillain–Barré Syndrome Post Hemorrhagic Stroke: Two Case Reports
title_full_unstemmed Fulminant Guillain–Barré Syndrome Post Hemorrhagic Stroke: Two Case Reports
title_short Fulminant Guillain–Barré Syndrome Post Hemorrhagic Stroke: Two Case Reports
title_sort fulminant guillain–barré syndrome post hemorrhagic stroke: two case reports
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162529/
https://www.ncbi.nlm.nih.gov/pubmed/34066316
http://dx.doi.org/10.3390/neurolint13020019
work_keys_str_mv AT abdulmanasameeh fulminantguillainbarresyndromeposthemorrhagicstroketwocasereports
AT alzahraninaif fulminantguillainbarresyndromeposthemorrhagicstroketwocasereports
AT sharahelyyahya fulminantguillainbarresyndromeposthemorrhagicstroketwocasereports
AT bashirshahid fulminantguillainbarresyndromeposthemorrhagicstroketwocasereports
AT malharbitalal fulminantguillainbarresyndromeposthemorrhagicstroketwocasereports