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Protamine Characterization by Top-Down Proteomics: Boosting Proteoform Identification with DBSCAN

Protamines replace histones as the main nuclear protein in the sperm cells of many species and play a crucial role in compacting the paternal genome. Human spermatozoa contain protamine 1 (P1) and the family of protamine 2 (P2) proteins. Alterations in protamine PTMs or the P1/P2 ratio may be associ...

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Detalles Bibliográficos
Autores principales:	Arauz-Garofalo, Gianluca, Jodar, Meritxell, Vilanova, Mar, de la Iglesia Rodriguez, Alberto, Castillo, Judit, Soler-Ventura, Ada, Oliva, Rafael, Vilaseca, Marta, Gay, Marina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162566/ https://www.ncbi.nlm.nih.gov/pubmed/33946530 http://dx.doi.org/10.3390/proteomes9020021

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