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scHiCTools: A computational toolbox for analyzing single-cell Hi-C data

Single-cell Hi-C (scHi-C) sequencing technologies allow us to investigate three-dimensional chromatin organization at the single-cell level. However, we still need computational tools to deal with the sparsity of the contact maps from single cells and embed single cells in a lower-dimensional Euclid...

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Detalles Bibliográficos
Autores principales: Li, Xinjun, Feng, Fan, Pu, Hongxi, Leung, Wai Yan, Liu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162587/
https://www.ncbi.nlm.nih.gov/pubmed/34003823
http://dx.doi.org/10.1371/journal.pcbi.1008978