A molecular approach to rationally constructing specific fluorogenic substrates for the detection of acetylcholinesterase activity in live cells, mice brains and tissues

Acetylcholinesterase (AChE) is an extremely critical hydrolase tightly associated with neurological diseases. Currently, developing specific substrates for imaging AChE activity still remains a great challenge due to the interference from butyrylcholinesterase (BChE) and carboxylesterase (CE). Herei...

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Detalles Bibliográficos
Autores principales: Wu, Xiaofeng, An, Jong Min, Shang, Jizhen, Huh, Eugene, Qi, Sujie, Lee, Eunhye, Li, Haidong, Kim, Gyoungmi, Ma, Huimin, Oh, Myung Sook, Kim, Dokyoung, Yoon, Juyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162927/
https://www.ncbi.nlm.nih.gov/pubmed/34094370
http://dx.doi.org/10.1039/d0sc04213g

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