LDL-mimetic lipid nanoparticles prepared by surface KAT ligation for in vivo MRI of atherosclerosis

Low-density lipoprotein (LDL)-mimetic lipid nanoparticles (LNPs), decorated with MRI contrast agents and fluorescent dyes, were prepared by the covalent attachment of apolipoprotein-mimetic peptide (P), Gd(iii)-chelate (Gd), and sulforhodamine B (R) moieties on the LNP surface. The functionalized LN...

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Detalles Bibliográficos
Autores principales: Fracassi, Alessandro, Cao, Jianbo, Yoshizawa-Sugata, Naoko, Tóth, Éva, Archer, Corey, Gröninger, Olivier, Ricciotti, Emanuela, Tang, Soon Yew, Handschin, Stephan, Bourgeois, Jean-Pascal, Ray, Ankita, Liosi, Korinne, Oriana, Sean, Stark, Wendelin, Masai, Hisao, Zhou, Rong, Yamakoshi, Yoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162946/
https://www.ncbi.nlm.nih.gov/pubmed/34094421
http://dx.doi.org/10.1039/d0sc04106h

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