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Treatment of Localized and Locally Advanced, High-Risk Prostate Cancer: A Report From the First Prostate Cancer Consensus Conference for Developing Countries
PURPOSE: To generate and present survey results on important issues relevant to treatment and follow-up of localized and locally advanced, high-risk prostate cancer (PCa) focusing on developing countries. METHODS: A panel of 99 PCa experts developed more than 300 survey questions of which 67 questio...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162969/ https://www.ncbi.nlm.nih.gov/pubmed/33856890 http://dx.doi.org/10.1200/GO.20.00421 |
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author | Khauli, Raja Ferrigno, Robson Guimarães, Gustavo Bulbulan, Muhammad Uson Junior, Pedro Luiz Serrano Salvajoli, Bernardo Palhares, Daniel Moore Freitas Racy, Douglas Gil, Erlon de Arruda, Fernando Freire Lemos, Gustavo Caserta Carvalhal, Gustavo Franco de Carvalho, Icaro Thiago Martins, Igor Austin Fernandes Gimpel, Ivan Frederico Pinto Salvajoli, João Victor Chambo, José Luis Pontes Jr, José Filho, Leopoldo Alves Ribeiro Nogueira, Lucas Freitas, Marcelo Roberto Pereira Wroclawski, Marcelo Arap, Marco Antonio Sadi, Marcus Vinicius Coelho, Rafael Gadia, Rafael Roja, Rodrigo Antonio Ledezma de Moraes Hanriot, Rodrigo Baroni, Ronaldo Zequi, Stenio Nahas, William Carlos Alfer Jr, Wladimir Maluf, Fernando Cotait |
author_facet | Khauli, Raja Ferrigno, Robson Guimarães, Gustavo Bulbulan, Muhammad Uson Junior, Pedro Luiz Serrano Salvajoli, Bernardo Palhares, Daniel Moore Freitas Racy, Douglas Gil, Erlon de Arruda, Fernando Freire Lemos, Gustavo Caserta Carvalhal, Gustavo Franco de Carvalho, Icaro Thiago Martins, Igor Austin Fernandes Gimpel, Ivan Frederico Pinto Salvajoli, João Victor Chambo, José Luis Pontes Jr, José Filho, Leopoldo Alves Ribeiro Nogueira, Lucas Freitas, Marcelo Roberto Pereira Wroclawski, Marcelo Arap, Marco Antonio Sadi, Marcus Vinicius Coelho, Rafael Gadia, Rafael Roja, Rodrigo Antonio Ledezma de Moraes Hanriot, Rodrigo Baroni, Ronaldo Zequi, Stenio Nahas, William Carlos Alfer Jr, Wladimir Maluf, Fernando Cotait |
author_sort | Khauli, Raja |
collection | PubMed |
description | PURPOSE: To generate and present survey results on important issues relevant to treatment and follow-up of localized and locally advanced, high-risk prostate cancer (PCa) focusing on developing countries. METHODS: A panel of 99 PCa experts developed more than 300 survey questions of which 67 questions concern the main areas of interest of this article: treatment and follow-up of localized and locally advanced, high-risk PCa in developing countries. A larger panel of 99 international multidisciplinary cancer experts voted on these questions to create the recommendations for treatment and follow-up of localized and locally advanced, high-risk PCa in areas of limited resources discussed in this article. RESULTS: The panel voted publicly but anonymously on the predefined questions. Each question was deemed consensus if 75% or more of the full panel had selected a particular answer. These answers are based on panelist opinion and not on a literature review or meta-analysis. For questions that refer to an area of limited resources, the recommendations considered cost-effectiveness as well as the possible therapies with easier and greater access. Each question had five to seven relevant answers including two nonanswers. Results were tabulated in real time. CONCLUSION: The voting results and recommendations presented in this article can guide physicians managing localized and locally advanced, high-risk PCa in areas of limited resources. Individual clinical decision making should be supported by available data; however, as guidelines for treatment of localized and locally advanced, high-risk PCa in developing countries have not been defined, this article will serve as a point of reference when confronted with this disease. |
format | Online Article Text |
id | pubmed-8162969 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-81629692021-06-01 Treatment of Localized and Locally Advanced, High-Risk Prostate Cancer: A Report From the First Prostate Cancer Consensus Conference for Developing Countries Khauli, Raja Ferrigno, Robson Guimarães, Gustavo Bulbulan, Muhammad Uson Junior, Pedro Luiz Serrano Salvajoli, Bernardo Palhares, Daniel Moore Freitas Racy, Douglas Gil, Erlon de Arruda, Fernando Freire Lemos, Gustavo Caserta Carvalhal, Gustavo Franco de Carvalho, Icaro Thiago Martins, Igor Austin Fernandes Gimpel, Ivan Frederico Pinto Salvajoli, João Victor Chambo, José Luis Pontes Jr, José Filho, Leopoldo Alves Ribeiro Nogueira, Lucas Freitas, Marcelo Roberto Pereira Wroclawski, Marcelo Arap, Marco Antonio Sadi, Marcus Vinicius Coelho, Rafael Gadia, Rafael Roja, Rodrigo Antonio Ledezma de Moraes Hanriot, Rodrigo Baroni, Ronaldo Zequi, Stenio Nahas, William Carlos Alfer Jr, Wladimir Maluf, Fernando Cotait JCO Glob Oncol SPECIAL ARTICLES PURPOSE: To generate and present survey results on important issues relevant to treatment and follow-up of localized and locally advanced, high-risk prostate cancer (PCa) focusing on developing countries. METHODS: A panel of 99 PCa experts developed more than 300 survey questions of which 67 questions concern the main areas of interest of this article: treatment and follow-up of localized and locally advanced, high-risk PCa in developing countries. A larger panel of 99 international multidisciplinary cancer experts voted on these questions to create the recommendations for treatment and follow-up of localized and locally advanced, high-risk PCa in areas of limited resources discussed in this article. RESULTS: The panel voted publicly but anonymously on the predefined questions. Each question was deemed consensus if 75% or more of the full panel had selected a particular answer. These answers are based on panelist opinion and not on a literature review or meta-analysis. For questions that refer to an area of limited resources, the recommendations considered cost-effectiveness as well as the possible therapies with easier and greater access. Each question had five to seven relevant answers including two nonanswers. Results were tabulated in real time. CONCLUSION: The voting results and recommendations presented in this article can guide physicians managing localized and locally advanced, high-risk PCa in areas of limited resources. Individual clinical decision making should be supported by available data; however, as guidelines for treatment of localized and locally advanced, high-risk PCa in developing countries have not been defined, this article will serve as a point of reference when confronted with this disease. Wolters Kluwer Health 2021-04-15 /pmc/articles/PMC8162969/ /pubmed/33856890 http://dx.doi.org/10.1200/GO.20.00421 Text en © 2021 by American Society of Clinical Oncology https://creativecommons.org/licenses/by/4.0/Licensed under the Creative Commons Attribution 4.0 License: https://creativecommons.org/licenses/by/4.0/ |
spellingShingle | SPECIAL ARTICLES Khauli, Raja Ferrigno, Robson Guimarães, Gustavo Bulbulan, Muhammad Uson Junior, Pedro Luiz Serrano Salvajoli, Bernardo Palhares, Daniel Moore Freitas Racy, Douglas Gil, Erlon de Arruda, Fernando Freire Lemos, Gustavo Caserta Carvalhal, Gustavo Franco de Carvalho, Icaro Thiago Martins, Igor Austin Fernandes Gimpel, Ivan Frederico Pinto Salvajoli, João Victor Chambo, José Luis Pontes Jr, José Filho, Leopoldo Alves Ribeiro Nogueira, Lucas Freitas, Marcelo Roberto Pereira Wroclawski, Marcelo Arap, Marco Antonio Sadi, Marcus Vinicius Coelho, Rafael Gadia, Rafael Roja, Rodrigo Antonio Ledezma de Moraes Hanriot, Rodrigo Baroni, Ronaldo Zequi, Stenio Nahas, William Carlos Alfer Jr, Wladimir Maluf, Fernando Cotait Treatment of Localized and Locally Advanced, High-Risk Prostate Cancer: A Report From the First Prostate Cancer Consensus Conference for Developing Countries |
title | Treatment of Localized and Locally Advanced, High-Risk Prostate Cancer: A Report From the First Prostate Cancer Consensus Conference for Developing Countries |
title_full | Treatment of Localized and Locally Advanced, High-Risk Prostate Cancer: A Report From the First Prostate Cancer Consensus Conference for Developing Countries |
title_fullStr | Treatment of Localized and Locally Advanced, High-Risk Prostate Cancer: A Report From the First Prostate Cancer Consensus Conference for Developing Countries |
title_full_unstemmed | Treatment of Localized and Locally Advanced, High-Risk Prostate Cancer: A Report From the First Prostate Cancer Consensus Conference for Developing Countries |
title_short | Treatment of Localized and Locally Advanced, High-Risk Prostate Cancer: A Report From the First Prostate Cancer Consensus Conference for Developing Countries |
title_sort | treatment of localized and locally advanced, high-risk prostate cancer: a report from the first prostate cancer consensus conference for developing countries |
topic | SPECIAL ARTICLES |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162969/ https://www.ncbi.nlm.nih.gov/pubmed/33856890 http://dx.doi.org/10.1200/GO.20.00421 |
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