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Accelerated microdroplet synthesis of benzimidazoles by nucleophilic addition to protonated carboxylic acids
We report a metal-free novel route for the accelerated synthesis of benzimidazole and its derivatives in the ambient atmosphere. The synthetic procedure involves 1,2-aromatic diamines and alkyl or aryl carboxylic acids reacting in electrostatically charged microdroplets generated using a nano-electr...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163001/ https://www.ncbi.nlm.nih.gov/pubmed/34094463 http://dx.doi.org/10.1039/d0sc02467h |