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Geriatric Neuro-Oncology in the Middle East: A Sultanate of Oman Experience

Brain tumors are primary or metastatic malignancies of the central nervous system (CNS) with significant morbidity and mortality. The overall prevalence of cancer including brain cancer has increased by more than 10% according to the National Institute of cancer statistics. The average percent incre...

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Autores principales: Al-Taei, Omar, Al-Mirza, Abdulrahman, Al-Saadi, Tariq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163002/
https://www.ncbi.nlm.nih.gov/pubmed/34071170
http://dx.doi.org/10.3390/neurolint13020024
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author Al-Taei, Omar
Al-Mirza, Abdulrahman
Al-Saadi, Tariq
author_facet Al-Taei, Omar
Al-Mirza, Abdulrahman
Al-Saadi, Tariq
author_sort Al-Taei, Omar
collection PubMed
description Brain tumors are primary or metastatic malignancies of the central nervous system (CNS) with significant morbidity and mortality. The overall prevalence of cancer including brain cancer has increased by more than 10% according to the National Institute of cancer statistics. The average percent increase in primary brain tumor incidence for ages 75–79, 80–84, and 85 and older were 7%, 20.4%, and 23.4%, respectively. This manuscript describes a retrospective study of geriatric cases admitted to the Neurosurgical Department in Khoula Hospital (KH) and diagnosed with brain cancer from 1 January 2016 to 31 December 2019. Of the study cohort, 58.5% were more than 75 years of age. The male-to-female ratio was (1:1.1). Meningiomas are found to be the commonest tumor (52.8%) followed by glioblastoma (GBM) (18.9%). Most of the patients had a Glasgow coma scale (GCS) score of 14–15 on admission (69.9%). Patients diagnosed with a non-meningioma tumor had lower GCS score on admission compared to meningioma patients with statistical significance (p = 0.04). Also, there was a significant difference between the length of stay (LOS) and the type of intervention (surgical vs. conservative), in which patients received a conservative type of management found to have a shorter length of stay (LOS) compared with the patients who underwent surgical intervention (p < 0.005). In Oman, the number of geriatric oncology cases remained stable over the 4 years. The incidence of geriatric neuro-oncology cases was higher in patients aged more than 75 years of age. Finally, the GCS score was affected by the type of tumor. The length of stay varies according to the treatment administered. Special care must be taken when dealing with geriatric neuro-oncological cases due to the high potential rate of mortality and morbidity among those group, and a more holistic approach is recommended as an essential need to evaluate the overall situation of those patients and manage them accordingly.
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spelling pubmed-81630022021-05-29 Geriatric Neuro-Oncology in the Middle East: A Sultanate of Oman Experience Al-Taei, Omar Al-Mirza, Abdulrahman Al-Saadi, Tariq Neurol Int Communication Brain tumors are primary or metastatic malignancies of the central nervous system (CNS) with significant morbidity and mortality. The overall prevalence of cancer including brain cancer has increased by more than 10% according to the National Institute of cancer statistics. The average percent increase in primary brain tumor incidence for ages 75–79, 80–84, and 85 and older were 7%, 20.4%, and 23.4%, respectively. This manuscript describes a retrospective study of geriatric cases admitted to the Neurosurgical Department in Khoula Hospital (KH) and diagnosed with brain cancer from 1 January 2016 to 31 December 2019. Of the study cohort, 58.5% were more than 75 years of age. The male-to-female ratio was (1:1.1). Meningiomas are found to be the commonest tumor (52.8%) followed by glioblastoma (GBM) (18.9%). Most of the patients had a Glasgow coma scale (GCS) score of 14–15 on admission (69.9%). Patients diagnosed with a non-meningioma tumor had lower GCS score on admission compared to meningioma patients with statistical significance (p = 0.04). Also, there was a significant difference between the length of stay (LOS) and the type of intervention (surgical vs. conservative), in which patients received a conservative type of management found to have a shorter length of stay (LOS) compared with the patients who underwent surgical intervention (p < 0.005). In Oman, the number of geriatric oncology cases remained stable over the 4 years. The incidence of geriatric neuro-oncology cases was higher in patients aged more than 75 years of age. Finally, the GCS score was affected by the type of tumor. The length of stay varies according to the treatment administered. Special care must be taken when dealing with geriatric neuro-oncological cases due to the high potential rate of mortality and morbidity among those group, and a more holistic approach is recommended as an essential need to evaluate the overall situation of those patients and manage them accordingly. MDPI 2021-05-28 /pmc/articles/PMC8163002/ /pubmed/34071170 http://dx.doi.org/10.3390/neurolint13020024 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Al-Taei, Omar
Al-Mirza, Abdulrahman
Al-Saadi, Tariq
Geriatric Neuro-Oncology in the Middle East: A Sultanate of Oman Experience
title Geriatric Neuro-Oncology in the Middle East: A Sultanate of Oman Experience
title_full Geriatric Neuro-Oncology in the Middle East: A Sultanate of Oman Experience
title_fullStr Geriatric Neuro-Oncology in the Middle East: A Sultanate of Oman Experience
title_full_unstemmed Geriatric Neuro-Oncology in the Middle East: A Sultanate of Oman Experience
title_short Geriatric Neuro-Oncology in the Middle East: A Sultanate of Oman Experience
title_sort geriatric neuro-oncology in the middle east: a sultanate of oman experience
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163002/
https://www.ncbi.nlm.nih.gov/pubmed/34071170
http://dx.doi.org/10.3390/neurolint13020024
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