Chemical synthesis and biological activity of peptides incorporating an ether bridge as a surrogate for a disulfide bond

Disulfide bridges contribute to the definition and rigidity of polypeptides, but they are inherently unstable in reducing environments and in the presence of isomerases and nucleophiles. Strategies to address these deficiencies, ideally without significantly perturbing the structure of the polypepti...

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Detalles Bibliográficos
Autores principales: Zhao, Rui, Shi, Pan, Chen, Junyou, Sun, Shuaishuai, Chen, Jingnan, Cui, Jibin, Wu, Fangming, Fang, Gemin, Tian, Changlin, Shi, Jing, Bierer, Donald, Liu, Lei, Li, Yi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163063/
https://www.ncbi.nlm.nih.gov/pubmed/34094161
http://dx.doi.org/10.1039/d0sc02374d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163063/
https://www.ncbi.nlm.nih.gov/pubmed/34094161
http://dx.doi.org/10.1039/d0sc02374d

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