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Reduced Bacterial Counts from a Sewage Treatment Plant but Increased Counts and Antibiotic Resistance in the Recipient Stream in Accra, Ghana—A Cross-Sectional Study

Wastewater treatment plants receive sewage containing high concentrations of bacteria and antibiotics. We assessed bacterial counts and their antibiotic resistance patterns in water from (a) influents and effluents of the Legon sewage treatment plant (STP) in Accra, Ghana and (b) upstream, outfall,...

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Autores principales: Adomako, Lady A. B., Yirenya-Tawiah, Dzidzo, Nukpezah, Daniel, Abrahamya, Arpine, Labi, Appiah-Korang, Grigoryan, Ruzanna, Ahmed, Hawa, Owusu-Danquah, Josiah, Annang, Ted Yemoh, Banu, Regina A., Osei-Atweneboana, Mike Y., Timire, Collins, Tweya, Hanock, Ackon, Stephen E. D., Nartey, Emmanuel, Zachariah, Rony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163181/
https://www.ncbi.nlm.nih.gov/pubmed/34068850
http://dx.doi.org/10.3390/tropicalmed6020079
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author Adomako, Lady A. B.
Yirenya-Tawiah, Dzidzo
Nukpezah, Daniel
Abrahamya, Arpine
Labi, Appiah-Korang
Grigoryan, Ruzanna
Ahmed, Hawa
Owusu-Danquah, Josiah
Annang, Ted Yemoh
Banu, Regina A.
Osei-Atweneboana, Mike Y.
Timire, Collins
Tweya, Hanock
Ackon, Stephen E. D.
Nartey, Emmanuel
Zachariah, Rony
author_facet Adomako, Lady A. B.
Yirenya-Tawiah, Dzidzo
Nukpezah, Daniel
Abrahamya, Arpine
Labi, Appiah-Korang
Grigoryan, Ruzanna
Ahmed, Hawa
Owusu-Danquah, Josiah
Annang, Ted Yemoh
Banu, Regina A.
Osei-Atweneboana, Mike Y.
Timire, Collins
Tweya, Hanock
Ackon, Stephen E. D.
Nartey, Emmanuel
Zachariah, Rony
author_sort Adomako, Lady A. B.
collection PubMed
description Wastewater treatment plants receive sewage containing high concentrations of bacteria and antibiotics. We assessed bacterial counts and their antibiotic resistance patterns in water from (a) influents and effluents of the Legon sewage treatment plant (STP) in Accra, Ghana and (b) upstream, outfall, and downstream in the recipient Onyasia stream. We conducted a cross-sectional study of quality-controlled water testing (January–June 2018). In STP effluents, mean bacterial counts (colony-forming units/100 mL) had reduced E. coli (99.9% reduction; 102,266,667 to 710), A. hydrophila (98.8%; 376,333 to 9603), and P. aeruginosa (99.5%; 5,666,667 to 1550). Antibiotic resistance was significantly reduced for tetracycline, ciprofloxacin, cefuroxime, and ceftazidime and increased for gentamicin, amoxicillin/clavulanate, and imipenem. The highest levels were for amoxicillin/clavulanate (50–97%) and aztreonam (33%). Bacterial counts increased by 98.8% downstream compared to the sewage outfall and were predominated by E. coli, implying intense fecal contamination from other sources. There was a progressive increase in antibiotic resistance from upstream, to outfall, to downstream. The highest resistance was for amoxicillin/clavulanate (80–83%), cefuroxime (47–73%), aztreonam (53%), and ciprofloxacin (40%). The STP is efficient in reducing bacterial counts and thus reducing environmental contamination. The recipient stream is contaminated with antibiotic-resistant bacteria listed as critically important for human use, which needs addressing.
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spelling pubmed-81631812021-05-29 Reduced Bacterial Counts from a Sewage Treatment Plant but Increased Counts and Antibiotic Resistance in the Recipient Stream in Accra, Ghana—A Cross-Sectional Study Adomako, Lady A. B. Yirenya-Tawiah, Dzidzo Nukpezah, Daniel Abrahamya, Arpine Labi, Appiah-Korang Grigoryan, Ruzanna Ahmed, Hawa Owusu-Danquah, Josiah Annang, Ted Yemoh Banu, Regina A. Osei-Atweneboana, Mike Y. Timire, Collins Tweya, Hanock Ackon, Stephen E. D. Nartey, Emmanuel Zachariah, Rony Trop Med Infect Dis Article Wastewater treatment plants receive sewage containing high concentrations of bacteria and antibiotics. We assessed bacterial counts and their antibiotic resistance patterns in water from (a) influents and effluents of the Legon sewage treatment plant (STP) in Accra, Ghana and (b) upstream, outfall, and downstream in the recipient Onyasia stream. We conducted a cross-sectional study of quality-controlled water testing (January–June 2018). In STP effluents, mean bacterial counts (colony-forming units/100 mL) had reduced E. coli (99.9% reduction; 102,266,667 to 710), A. hydrophila (98.8%; 376,333 to 9603), and P. aeruginosa (99.5%; 5,666,667 to 1550). Antibiotic resistance was significantly reduced for tetracycline, ciprofloxacin, cefuroxime, and ceftazidime and increased for gentamicin, amoxicillin/clavulanate, and imipenem. The highest levels were for amoxicillin/clavulanate (50–97%) and aztreonam (33%). Bacterial counts increased by 98.8% downstream compared to the sewage outfall and were predominated by E. coli, implying intense fecal contamination from other sources. There was a progressive increase in antibiotic resistance from upstream, to outfall, to downstream. The highest resistance was for amoxicillin/clavulanate (80–83%), cefuroxime (47–73%), aztreonam (53%), and ciprofloxacin (40%). The STP is efficient in reducing bacterial counts and thus reducing environmental contamination. The recipient stream is contaminated with antibiotic-resistant bacteria listed as critically important for human use, which needs addressing. MDPI 2021-05-14 /pmc/articles/PMC8163181/ /pubmed/34068850 http://dx.doi.org/10.3390/tropicalmed6020079 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Adomako, Lady A. B.
Yirenya-Tawiah, Dzidzo
Nukpezah, Daniel
Abrahamya, Arpine
Labi, Appiah-Korang
Grigoryan, Ruzanna
Ahmed, Hawa
Owusu-Danquah, Josiah
Annang, Ted Yemoh
Banu, Regina A.
Osei-Atweneboana, Mike Y.
Timire, Collins
Tweya, Hanock
Ackon, Stephen E. D.
Nartey, Emmanuel
Zachariah, Rony
Reduced Bacterial Counts from a Sewage Treatment Plant but Increased Counts and Antibiotic Resistance in the Recipient Stream in Accra, Ghana—A Cross-Sectional Study
title Reduced Bacterial Counts from a Sewage Treatment Plant but Increased Counts and Antibiotic Resistance in the Recipient Stream in Accra, Ghana—A Cross-Sectional Study
title_full Reduced Bacterial Counts from a Sewage Treatment Plant but Increased Counts and Antibiotic Resistance in the Recipient Stream in Accra, Ghana—A Cross-Sectional Study
title_fullStr Reduced Bacterial Counts from a Sewage Treatment Plant but Increased Counts and Antibiotic Resistance in the Recipient Stream in Accra, Ghana—A Cross-Sectional Study
title_full_unstemmed Reduced Bacterial Counts from a Sewage Treatment Plant but Increased Counts and Antibiotic Resistance in the Recipient Stream in Accra, Ghana—A Cross-Sectional Study
title_short Reduced Bacterial Counts from a Sewage Treatment Plant but Increased Counts and Antibiotic Resistance in the Recipient Stream in Accra, Ghana—A Cross-Sectional Study
title_sort reduced bacterial counts from a sewage treatment plant but increased counts and antibiotic resistance in the recipient stream in accra, ghana—a cross-sectional study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163181/
https://www.ncbi.nlm.nih.gov/pubmed/34068850
http://dx.doi.org/10.3390/tropicalmed6020079
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