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Leptospirosis in Ruminants in Yogyakarta, Indonesia: A Serological Survey with Mixed Methods to Identify Risk Factors

Leptospirosis is a zoonotic disease occurring worldwide with reproductive symptoms and production losses in livestock, while humans can suffer fatal renal failure. In Yogyakarta Special Province, Indonesia, there have been several outbreaks with high case fatality, demonstrating the public health im...

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Autores principales: Widiasih, Dyah Ayu, Lindahl, Johanna Frida, Artama, Wayan T., Sutomo, Adi Heru, Kutanegara, Pande Made, Mulyani, Guntari Titik, Widodo, Estu, Djohan, Tjut Sugandawaty, Unger, Fred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163187/
https://www.ncbi.nlm.nih.gov/pubmed/34065182
http://dx.doi.org/10.3390/tropicalmed6020084
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author Widiasih, Dyah Ayu
Lindahl, Johanna Frida
Artama, Wayan T.
Sutomo, Adi Heru
Kutanegara, Pande Made
Mulyani, Guntari Titik
Widodo, Estu
Djohan, Tjut Sugandawaty
Unger, Fred
author_facet Widiasih, Dyah Ayu
Lindahl, Johanna Frida
Artama, Wayan T.
Sutomo, Adi Heru
Kutanegara, Pande Made
Mulyani, Guntari Titik
Widodo, Estu
Djohan, Tjut Sugandawaty
Unger, Fred
author_sort Widiasih, Dyah Ayu
collection PubMed
description Leptospirosis is a zoonotic disease occurring worldwide with reproductive symptoms and production losses in livestock, while humans can suffer fatal renal failure. In Yogyakarta Special Province, Indonesia, there have been several outbreaks with high case fatality, demonstrating the public health importance, but there is limited understanding of the epidemiology. This study used an EcoHealth approach to ensure transdisciplinarity and community participation. Seroprevalence of Leptospira in animals was studied between October 2011 and May 2013 in 15 villages. Serum samples from 1404 cattle and 60 small ruminants were screened by a Microscopic Agglutination Test (MAT), first in pools, and then the individual positive samples were identified. Focus group discussions including farmers, village officials, and official stakeholders were used to explore knowledge and behavior of zoonotic diseases, particularly leptospirosis. Two small ruminants were seropositive for Leptospira icterohemorrhagiae. From the cattle, 3.7% were seropositive, and the most common serovars were Leptospira hardjo, followed by L. icterohemorrhagiae. Out of all farms, 5.6% had at least one positive cattle. Risk factor analyses showed that the risk of the farm being seropositive increased if the farmer used water from an open source, or if farming was not the main occupation. This study showed the presence of Leptospira spp. in ruminants in Yogyakarta and identified use of open water as a risk factor for the livestock. We also observed that the knowledge related to leptospirosis was low, and risky farm management practices were commonly employed.
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spelling pubmed-81631872021-05-29 Leptospirosis in Ruminants in Yogyakarta, Indonesia: A Serological Survey with Mixed Methods to Identify Risk Factors Widiasih, Dyah Ayu Lindahl, Johanna Frida Artama, Wayan T. Sutomo, Adi Heru Kutanegara, Pande Made Mulyani, Guntari Titik Widodo, Estu Djohan, Tjut Sugandawaty Unger, Fred Trop Med Infect Dis Article Leptospirosis is a zoonotic disease occurring worldwide with reproductive symptoms and production losses in livestock, while humans can suffer fatal renal failure. In Yogyakarta Special Province, Indonesia, there have been several outbreaks with high case fatality, demonstrating the public health importance, but there is limited understanding of the epidemiology. This study used an EcoHealth approach to ensure transdisciplinarity and community participation. Seroprevalence of Leptospira in animals was studied between October 2011 and May 2013 in 15 villages. Serum samples from 1404 cattle and 60 small ruminants were screened by a Microscopic Agglutination Test (MAT), first in pools, and then the individual positive samples were identified. Focus group discussions including farmers, village officials, and official stakeholders were used to explore knowledge and behavior of zoonotic diseases, particularly leptospirosis. Two small ruminants were seropositive for Leptospira icterohemorrhagiae. From the cattle, 3.7% were seropositive, and the most common serovars were Leptospira hardjo, followed by L. icterohemorrhagiae. Out of all farms, 5.6% had at least one positive cattle. Risk factor analyses showed that the risk of the farm being seropositive increased if the farmer used water from an open source, or if farming was not the main occupation. This study showed the presence of Leptospira spp. in ruminants in Yogyakarta and identified use of open water as a risk factor for the livestock. We also observed that the knowledge related to leptospirosis was low, and risky farm management practices were commonly employed. MDPI 2021-05-20 /pmc/articles/PMC8163187/ /pubmed/34065182 http://dx.doi.org/10.3390/tropicalmed6020084 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Widiasih, Dyah Ayu
Lindahl, Johanna Frida
Artama, Wayan T.
Sutomo, Adi Heru
Kutanegara, Pande Made
Mulyani, Guntari Titik
Widodo, Estu
Djohan, Tjut Sugandawaty
Unger, Fred
Leptospirosis in Ruminants in Yogyakarta, Indonesia: A Serological Survey with Mixed Methods to Identify Risk Factors
title Leptospirosis in Ruminants in Yogyakarta, Indonesia: A Serological Survey with Mixed Methods to Identify Risk Factors
title_full Leptospirosis in Ruminants in Yogyakarta, Indonesia: A Serological Survey with Mixed Methods to Identify Risk Factors
title_fullStr Leptospirosis in Ruminants in Yogyakarta, Indonesia: A Serological Survey with Mixed Methods to Identify Risk Factors
title_full_unstemmed Leptospirosis in Ruminants in Yogyakarta, Indonesia: A Serological Survey with Mixed Methods to Identify Risk Factors
title_short Leptospirosis in Ruminants in Yogyakarta, Indonesia: A Serological Survey with Mixed Methods to Identify Risk Factors
title_sort leptospirosis in ruminants in yogyakarta, indonesia: a serological survey with mixed methods to identify risk factors
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163187/
https://www.ncbi.nlm.nih.gov/pubmed/34065182
http://dx.doi.org/10.3390/tropicalmed6020084
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