Organophotoredox/palladium dual catalytic decarboxylative Csp(3)–Csp(3) coupling of carboxylic acids and π-electrophiles

A dual catalytic decarboxylative allylation and benzylation method for the construction of new C(sp(3))–C(sp(3)) bonds between readily available carboxylic acids and functionally diverse carbonate electrophiles has been developed. The new process is mild, operationally simple, and has greatly improv...

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Detalles Bibliográficos
Autores principales: Cartwright, Kaitie C., Tunge, Jon A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163213/
https://www.ncbi.nlm.nih.gov/pubmed/34094175
http://dx.doi.org/10.1039/d0sc02609c
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author Cartwright, Kaitie C.
Tunge, Jon A.
author_facet Cartwright, Kaitie C.
Tunge, Jon A.
author_sort Cartwright, Kaitie C.
collection PubMed
description A dual catalytic decarboxylative allylation and benzylation method for the construction of new C(sp(3))–C(sp(3)) bonds between readily available carboxylic acids and functionally diverse carbonate electrophiles has been developed. The new process is mild, operationally simple, and has greatly improved upon the efficiency and generality of previous methodology. In addition, new insights into the reaction mechanism have been realized and provide further understanding of the harnessed reactivity.
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spelling pubmed-81632132021-06-04 Organophotoredox/palladium dual catalytic decarboxylative Csp(3)–Csp(3) coupling of carboxylic acids and π-electrophiles Cartwright, Kaitie C. Tunge, Jon A. Chem Sci Chemistry A dual catalytic decarboxylative allylation and benzylation method for the construction of new C(sp(3))–C(sp(3)) bonds between readily available carboxylic acids and functionally diverse carbonate electrophiles has been developed. The new process is mild, operationally simple, and has greatly improved upon the efficiency and generality of previous methodology. In addition, new insights into the reaction mechanism have been realized and provide further understanding of the harnessed reactivity. The Royal Society of Chemistry 2020-07-16 /pmc/articles/PMC8163213/ /pubmed/34094175 http://dx.doi.org/10.1039/d0sc02609c Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Cartwright, Kaitie C.
Tunge, Jon A.
Organophotoredox/palladium dual catalytic decarboxylative Csp(3)–Csp(3) coupling of carboxylic acids and π-electrophiles
title Organophotoredox/palladium dual catalytic decarboxylative Csp(3)–Csp(3) coupling of carboxylic acids and π-electrophiles
title_full Organophotoredox/palladium dual catalytic decarboxylative Csp(3)–Csp(3) coupling of carboxylic acids and π-electrophiles
title_fullStr Organophotoredox/palladium dual catalytic decarboxylative Csp(3)–Csp(3) coupling of carboxylic acids and π-electrophiles
title_full_unstemmed Organophotoredox/palladium dual catalytic decarboxylative Csp(3)–Csp(3) coupling of carboxylic acids and π-electrophiles
title_short Organophotoredox/palladium dual catalytic decarboxylative Csp(3)–Csp(3) coupling of carboxylic acids and π-electrophiles
title_sort organophotoredox/palladium dual catalytic decarboxylative csp(3)–csp(3) coupling of carboxylic acids and π-electrophiles
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163213/
https://www.ncbi.nlm.nih.gov/pubmed/34094175
http://dx.doi.org/10.1039/d0sc02609c
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AT tungejona organophotoredoxpalladiumdualcatalyticdecarboxylativecsp3csp3couplingofcarboxylicacidsandpelectrophiles

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