Palladium-catalyzed direct asymmetric C–H bond functionalization enabled by the directing group strategy

In the past decade, selective C–C and C-heteroatom bond construction through palladium-catalyzed direct C–H bond functionalization has been extensively studied by employing a variety of directing groups. Within this category, direct asymmetric C(sp(2))–H and C(sp(3))–H activation for the constructio...

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Detalles Bibliográficos
Autores principales: Yang, Ke, Song, Mengjie, Liu, Hao, Ge, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163320/
https://www.ncbi.nlm.nih.gov/pubmed/34123236
http://dx.doi.org/10.1039/d0sc03052j
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author Yang, Ke
Song, Mengjie
Liu, Hao
Ge, Haibo
author_facet Yang, Ke
Song, Mengjie
Liu, Hao
Ge, Haibo
author_sort Yang, Ke
collection PubMed
description In the past decade, selective C–C and C-heteroatom bond construction through palladium-catalyzed direct C–H bond functionalization has been extensively studied by employing a variety of directing groups. Within this category, direct asymmetric C(sp(2))–H and C(sp(3))–H activation for the construction of highly enantiomerically enriched skeletons still progressed at a slow pace. This minireview briefly introduces the major advances in the field for palladium-catalyzed direct asymmetric C–H bond functionalization via the directing group strategy.
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spelling pubmed-81633202021-06-11 Palladium-catalyzed direct asymmetric C–H bond functionalization enabled by the directing group strategy Yang, Ke Song, Mengjie Liu, Hao Ge, Haibo Chem Sci Chemistry In the past decade, selective C–C and C-heteroatom bond construction through palladium-catalyzed direct C–H bond functionalization has been extensively studied by employing a variety of directing groups. Within this category, direct asymmetric C(sp(2))–H and C(sp(3))–H activation for the construction of highly enantiomerically enriched skeletons still progressed at a slow pace. This minireview briefly introduces the major advances in the field for palladium-catalyzed direct asymmetric C–H bond functionalization via the directing group strategy. The Royal Society of Chemistry 2020-07-09 /pmc/articles/PMC8163320/ /pubmed/34123236 http://dx.doi.org/10.1039/d0sc03052j Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Yang, Ke
Song, Mengjie
Liu, Hao
Ge, Haibo
Palladium-catalyzed direct asymmetric C–H bond functionalization enabled by the directing group strategy
title Palladium-catalyzed direct asymmetric C–H bond functionalization enabled by the directing group strategy
title_full Palladium-catalyzed direct asymmetric C–H bond functionalization enabled by the directing group strategy
title_fullStr Palladium-catalyzed direct asymmetric C–H bond functionalization enabled by the directing group strategy
title_full_unstemmed Palladium-catalyzed direct asymmetric C–H bond functionalization enabled by the directing group strategy
title_short Palladium-catalyzed direct asymmetric C–H bond functionalization enabled by the directing group strategy
title_sort palladium-catalyzed direct asymmetric c–h bond functionalization enabled by the directing group strategy
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163320/
https://www.ncbi.nlm.nih.gov/pubmed/34123236
http://dx.doi.org/10.1039/d0sc03052j
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AT songmengjie palladiumcatalyzeddirectasymmetricchbondfunctionalizationenabledbythedirectinggroupstrategy
AT liuhao palladiumcatalyzeddirectasymmetricchbondfunctionalizationenabledbythedirectinggroupstrategy
AT gehaibo palladiumcatalyzeddirectasymmetricchbondfunctionalizationenabledbythedirectinggroupstrategy

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