Chemical synthesis and immunological evaluation of entirely carbohydrate conjugate Globo H-PS A1

An anticancer, entirely carbohydrate conjugate, Globo H-polysaccharide A1 (Globo H-PS A1), was chemically prepared and immunologically evaluated in C57BL/6 mice. Tumor associated carbohydrate antigen Globo H hexasaccharide was synthesized in an overall 7.8% yield employing a convergent [3 + 3] strat...

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Detalles Bibliográficos
Autores principales: Ghosh, Samir, Trabbic, Kevin R., Shi, Mengchao, Nishat, Sharmeen, Eradi, Pradheep, Kleski, Kristopher A., Andreana, Peter R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163331/
https://www.ncbi.nlm.nih.gov/pubmed/34123241
http://dx.doi.org/10.1039/d0sc04595k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163331/
https://www.ncbi.nlm.nih.gov/pubmed/34123241
http://dx.doi.org/10.1039/d0sc04595k

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