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Cerebral Venous Thrombosis and Its Clinical Diversity

Cerebral venous thrombosis (CVT) is a serious medical condition which is difficult to diagnose because of its wide range of clinical presentations. The symptoms can vary from an isolated headache to coma. Here, we present the case of a 76-year-old female patient with a history of immune thrombocytop...

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Autores principales: Ennis, Giovana, Domingues, Nelson, Silva Marques, Joana, Ribeiro, Pedro, Andrade, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163355/
https://www.ncbi.nlm.nih.gov/pubmed/34084677
http://dx.doi.org/10.7759/cureus.14750
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author Ennis, Giovana
Domingues, Nelson
Silva Marques, Joana
Ribeiro, Pedro
Andrade, Cristina
author_facet Ennis, Giovana
Domingues, Nelson
Silva Marques, Joana
Ribeiro, Pedro
Andrade, Cristina
author_sort Ennis, Giovana
collection PubMed
description Cerebral venous thrombosis (CVT) is a serious medical condition which is difficult to diagnose because of its wide range of clinical presentations. The symptoms can vary from an isolated headache to coma. Here, we present the case of a 76-year-old female patient with a history of immune thrombocytopenic purpura, arterial hypertension, and pulmonary embolism. The diagnosis of CVT was challenging because the initial form of disease presentation mimicked a transient ischemic attack (transient aphasia and right hemiparesis). Therapeutical decisions were also a challenge because, at the time of the diagnosis, the patient was suffering from severe thrombocytopenia (29 × 10(9)/L), which had to be taken into account. After multidisciplinary discussions, therapeutic subcutaneous enoxaparin was started, resulting in a progressive and significant neurological recovery. In presenting this case, our primary goal is to point out that CVT can be difficult to diagnose because of its wide range of clinical presentations. Headache (a symptom that was never present in this case) is the most frequent complaint, occurring in 90% of cases. Following diagnosis, an etiological study is required.
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spelling pubmed-81633552021-06-02 Cerebral Venous Thrombosis and Its Clinical Diversity Ennis, Giovana Domingues, Nelson Silva Marques, Joana Ribeiro, Pedro Andrade, Cristina Cureus Internal Medicine Cerebral venous thrombosis (CVT) is a serious medical condition which is difficult to diagnose because of its wide range of clinical presentations. The symptoms can vary from an isolated headache to coma. Here, we present the case of a 76-year-old female patient with a history of immune thrombocytopenic purpura, arterial hypertension, and pulmonary embolism. The diagnosis of CVT was challenging because the initial form of disease presentation mimicked a transient ischemic attack (transient aphasia and right hemiparesis). Therapeutical decisions were also a challenge because, at the time of the diagnosis, the patient was suffering from severe thrombocytopenia (29 × 10(9)/L), which had to be taken into account. After multidisciplinary discussions, therapeutic subcutaneous enoxaparin was started, resulting in a progressive and significant neurological recovery. In presenting this case, our primary goal is to point out that CVT can be difficult to diagnose because of its wide range of clinical presentations. Headache (a symptom that was never present in this case) is the most frequent complaint, occurring in 90% of cases. Following diagnosis, an etiological study is required. Cureus 2021-04-29 /pmc/articles/PMC8163355/ /pubmed/34084677 http://dx.doi.org/10.7759/cureus.14750 Text en Copyright © 2021, Ennis et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Ennis, Giovana
Domingues, Nelson
Silva Marques, Joana
Ribeiro, Pedro
Andrade, Cristina
Cerebral Venous Thrombosis and Its Clinical Diversity
title Cerebral Venous Thrombosis and Its Clinical Diversity
title_full Cerebral Venous Thrombosis and Its Clinical Diversity
title_fullStr Cerebral Venous Thrombosis and Its Clinical Diversity
title_full_unstemmed Cerebral Venous Thrombosis and Its Clinical Diversity
title_short Cerebral Venous Thrombosis and Its Clinical Diversity
title_sort cerebral venous thrombosis and its clinical diversity
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163355/
https://www.ncbi.nlm.nih.gov/pubmed/34084677
http://dx.doi.org/10.7759/cureus.14750
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