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Visible light driven deuteration of formyl C–H and hydridic C(sp(3))–H bonds in feedstock chemicals and pharmaceutical molecules

Deuterium labelled compounds are of significant importance in chemical mechanism investigations, mass spectrometric studies, diagnoses of drug metabolisms, and pharmaceutical discovery. Herein, we report an efficient hydrogen deuterium exchange reaction using deuterium oxide (D(2)O) as the deuterium...

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Detalles Bibliográficos
Autores principales: Kuang, Yulong, Cao, Hui, Tang, Haidi, Chew, Junhong, Chen, Wei, Shi, Xiangcheng, Wu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163369/
https://www.ncbi.nlm.nih.gov/pubmed/34123145
http://dx.doi.org/10.1039/d0sc02661a