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Visible light driven deuteration of formyl C–H and hydridic C(sp(3))–H bonds in feedstock chemicals and pharmaceutical molecules
Deuterium labelled compounds are of significant importance in chemical mechanism investigations, mass spectrometric studies, diagnoses of drug metabolisms, and pharmaceutical discovery. Herein, we report an efficient hydrogen deuterium exchange reaction using deuterium oxide (D(2)O) as the deuterium...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163369/ https://www.ncbi.nlm.nih.gov/pubmed/34123145 http://dx.doi.org/10.1039/d0sc02661a |