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Mechanistic insight into hydroxamate transfer reaction mimicking the inhibition of zinc-containing enzymes

A hydroxamate transfer reaction between metal complexes has been investigated by a combination of experimental and theoretical studies. A hydroxamate-bound cobalt(ii) complex bearing a tetradentate macrocyclic ligand, [Co(II)(TBDAP)(CH(3)C(–NHO)O)](+) (1), is prepared by the reduction of a hydroxima...

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Detalles Bibliográficos
Autores principales: Kwon, Nam, Suh, Jong-Min, Lim, Mi Hee, Hirao, Hajime, Cho, Jaeheung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163387/
https://www.ncbi.nlm.nih.gov/pubmed/34123156
http://dx.doi.org/10.1039/d0sc02676j