Cargando…
Understanding the factors controlling the photo-oxidation of natural DNA by enantiomerically pure intercalating ruthenium polypyridyl complexes through TA/TRIR studies with polydeoxynucleotides and mixed sequence oligodeoxynucleotides
Ruthenium polypyridyl complexes which can sensitise the photo-oxidation of nucleic acids and other biological molecules show potential for photo-therapeutic applications. In this article a combination of transient visible absorption (TrA) and time-resolved infra-red (TRIR) spectroscopy are used to c...
Autores principales: | Keane, Páraic M., O'Sullivan, Kyra, Poynton, Fergus E., Poulsen, Bjørn C., Sazanovich, Igor V., Towrie, Michael, Cardin, Christine J., Sun, Xue-Zhong, George, Michael W., Gunnlaugsson, Thorfinnur, Quinn, Susan J., Kelly, John M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163394/ https://www.ncbi.nlm.nih.gov/pubmed/34123120 http://dx.doi.org/10.1039/d0sc02413a |
Ejemplares similares
-
Reversal of a Single Base‐Pair Step Controls Guanine Photo‐Oxidation by an Intercalating Ruthenium(II) Dipyridophenazine Complex
por: Keane, Páraic M., et al.
Publicado: (2015) -
Direct observation by time-resolved infrared spectroscopy of the bright and the dark excited states of the [Ru(phen)(2)(dppz)](2+) light-switch compound in solution and when bound to DNA
por: Poynton, Fergus E., et al.
Publicado: (2016) -
Ruthenium
Polypyridyl Complex Bound to a Unimolecular
Chair-Form G-Quadruplex
por: McQuaid, Kane T., et al.
Publicado: (2022) -
Stabilization of Long-Looped i-Motif DNA by Polypyridyl Ruthenium Complexes
por: Pages, Benjamin J., et al.
Publicado: (2019) -
Adenine
Radical Cation Formation by a Ligand-Centered
Excited State of an Intercalated Chromium Polypyridyl Complex Leads
to Enhanced DNA Photo-oxidation
por: Baptista, Frederico A., et al.
Publicado: (2021)