A sustained type I IFN-neutrophil-IL-18 axis drives pathology during mucosal viral infection

Neutrophil responses against pathogens must be balanced between protection and immunopathology. Factors that determine these outcomes are not well-understood. In a mouse model of genital herpes simplex virus-2 (HSV-2) infection, which results in severe genital inflammation, antibody-mediated neutrop...

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Detalles Bibliográficos
Autores principales: Lebratti, Tania, Lim, Ying Shiang, Cofie, Adjoa, Andhey, Prabhakar, Jiang, Xiaoping, Scott, Jason, Fabbrizi, Maria Rita, Ozantürk, Ayşe Naz, Pham, Christine, Clemens, Regina, Artyomov, Maxim, Dinauer, Mary, Shin, Haina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163503/
https://www.ncbi.nlm.nih.gov/pubmed/34047696
http://dx.doi.org/10.7554/eLife.65762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163503/
https://www.ncbi.nlm.nih.gov/pubmed/34047696
http://dx.doi.org/10.7554/eLife.65762

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