Cargando…

PHAROH lncRNA regulates Myc translation in hepatocellular carcinoma via sequestering TIAR

Hepatocellular carcinoma, the most common type of liver malignancy, is one of the most lethal forms of cancer. We identified a long non-coding RNA, Gm19705, that is overexpressed in hepatocellular carcinoma and mouse embryonic stem cells. We named this RNA Pluripotency and Hepatocyte Associated RNA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Allen T, Berasain, Carmen, Bhatia, Sonam, Rivera, Keith, Liu, Bodu, Rigo, Frank, Pappin, Darryl J, Spector, David L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163507/ https://www.ncbi.nlm.nih.gov/pubmed/34002693 http://dx.doi.org/10.7554/eLife.68263

Ejemplares similares

MaTAR25 lncRNA regulates the Tensin1 gene to impact breast cancer progression
por: Chang, Kung-Chi, et al.
Publicado: (2020)

Depletion of NEAT1 lncRNA attenuates nucleolar stress by releasing sequestered P54nrb and PSF to facilitate c-Myc translation
por: Shen, Wen, et al.
Publicado: (2017)

LncRNA MT1JP functions as a tumor suppressor by interacting with TIAR to modulate the p53 pathway
por: Liu, Lihui, et al.
Publicado: (2016)

The molecular mechanisms of LncRNA-correlated PKM2 in cancer metabolism
por: Tao, Ting, et al.
Publicado: (2019)

RNA binding protein TIAR modulates HBV replication by tipping the balance of pgRNA translation
por: Zhang, Ting, et al.
Publicado: (2023)

LncRNA DANCR Promotes Lung Cancer by Sequestering miR-216a
por: Zhen, Qiang, et al.
Publicado: (2018)

Distinct binding properties of TIAR RRMs and linker region
por: Kim, Henry S., et al.
Publicado: (2013)

The prognostic value of lncRNA SNHG4 and its potential mechanism in liver cancer
por: Jiao, Yan, et al.
Publicado: (2020)

The role of EMT-related lncRNA in the process of triple-negative breast cancer metastasis
por: Zhang, Haomeng, et al.
Publicado: (2021)

lncRNA ATXN8OS promotes breast cancer by sequestering miR-204
por: Deng, Zhen, et al.
Publicado: (2019)

MYC‐activated lncRNA HNF1A‐AS1 overexpression facilitates glioma progression via cooperating with miR‐32‐5p/SOX4 axis
por: Wu, Jianheng, et al.
Publicado: (2020)

Novel DNA-binding properties of the RNA-binding protein TIAR
por: Suswam, Esther A., et al.
Publicado: (2005)

Autoantibodies to the TNF-α translational regulators TIA-1 and TIAR occur frequently in sera of patients with SLE and scleroderma
por: Jimenez-Boj, E, et al.
Publicado: (2002)

Targetting an LncRNA P5848-ENO1 axis inhibits tumor growth in hepatocellular carcinoma
por: Zhu, Xidan, et al.
Publicado: (2019)

Circulating lncRNA DANCR as a potential auxillary biomarker for the diagnosis and prognostic prediction of colorectal cancer
por: Shen, Xianjuan, et al.
Publicado: (2020)

Prognostic significance of lncRNA DANCR expression in human cancers: a systematic review and meta-analysis
por: Liu, Wei, et al.
Publicado: (2021)

Prognostic significance of LncRNA GHET1 expression in various cancers: a systematic review and meta-analysis
por: Ye, Jing, et al.
Publicado: (2019)

LncRNA AWPPH as a prognostic predictor in human cancers in Chinese population: evidence from meta-analysis
por: Li, Yongfeng, et al.
Publicado: (2021)

Different modes of interaction by TIAR and HuR with target RNA and DNA
por: Kim, Henry S., et al.
Publicado: (2011)

Impaired Embryonic Development in Mice Overexpressing the RNA-Binding Protein TIAR
por: Kharraz, Yacine, et al.
Publicado: (2010)

An Appraisal of the Tissue Injury and Repair (TIAR) Theory on the Pathogenesis of Endometriosis and Adenomyosis
por: Habiba, Marwan, et al.
Publicado: (2023)

LncRNA SNHG15 modulates gastric cancer tumorigenesis by impairing miR-506-5p expression
por: Chen, Zhiping, et al.
Publicado: (2021)

Screening key lncRNAs for human rectal adenocarcinoma based on lncRNA‐mRNA functional synergistic network
por: Zhu, Xiongwen, et al.
Publicado: (2019)

LncRNA DLX6-AS1 as a potential molecular biomarker in the clinicopathology and prognosis of various cancers: a meta-analysis
por: Tian, Shubo, et al.
Publicado: (2020)

Silencing lncRNA DUXAP8 inhibits lung adenocarcinoma progression by targeting miR-26b-5p
por: Liu, Yi, et al.
Publicado: (2021)

LncRNA SRA mediates cell migration, invasion, and progression of ovarian cancer via NOTCH signaling and epithelial–mesenchymal transition
por: Kim, Lee Kyung, et al.
Publicado: (2021)

The implication of lncRNA expression pattern and potential function of lncRNA RP4‐576H24.2 in acute myeloid leukemia
por: Zheng, Jifu, et al.
Publicado: (2019)

A novel lncRNA‐miRNA‐mRNA network analysis identified the hub lncRNA RP11‐159F24.1 in the pathogenesis of papillary thyroid cancer
por: Jiang, Wei, et al.
Publicado: (2018)

LncRNA TUG1 promotes the progression of colorectal cancer via the miR-138-5p/ZEB2 axis
por: Yan, Zhenkun, et al.
Publicado: (2020)

LncRNA NEAT1 promotes glioma cancer progression via regulation of miR-98-5p/BZW1
por: Li, Yabin, et al.
Publicado: (2021)

The asymmetrically segregating lncRNA cherub is required for transforming stem cells into malignant cells
por: Landskron, Lisa, et al.
Publicado: (2018)

LncRNA HOXA-AS2 promotes the progression of prostate cancer via targeting miR-509-3p/PBX3 axis
por: Xiao, Shangwen, et al.
Publicado: (2020)

LncRNA SNHG12 contributes proliferation, invasion and epithelial–mesenchymal transition of pancreatic cancer cells by absorbing miRNA-320b
por: Cao, Wei, et al.
Publicado: (2020)

LncRNA Sox2ot modulates the progression of thoracic aortic aneurysm by regulating miR-330-5p/Myh11
por: Xiao, Weizhang, et al.
Publicado: (2020)

LncRNA MCM3AP-AS1 inhibits cell proliferation in cervical squamous cell carcinoma by down-regulating miRNA-93
por: Lan, Liu, et al.
Publicado: (2020)

LncRNA GHET1 promotes cervical cancer progression through regulating AKT/mTOR and Wnt/β-catenin signaling pathways
por: Liu, Zhihui, et al.
Publicado: (2020)

β-Elemene suppresses tumor growth of diffuse large B-cell lymphoma through regulating lncRNA HULC-mediated apoptotic pathway
por: Hu, Tonglin, et al.
Publicado: (2020)

LncRNA HOTAIR contributes Taxol-resistance of hepatocellular carcinoma cells via activating AKT phosphorylation by down-regulating miR-34a
por: Duan, Yunfei, et al.
Publicado: (2020)

LncRNA LINC01503 aggravates the progression of cervical cancer through sponging miR-342-3p to mediate FXYD3 expression
por: Peng, Xing, et al.
Publicado: (2020)

Knockdown of LncRNA CRNDE suppresses proliferation and P-glycoprotein-mediated multidrug resistance in acute myelocytic leukemia through the Wnt/β-catenin pathway
por: Kang, Yiqing, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_01649uq9kf060a24kcnp8pesfu