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Mitophagy Impairment Aggravates Cisplatin-Induced Ototoxicity

Cisplatin is an efficacious anticancer agent, but its use is limited by ototoxicity and resultant irreversible sensorineural hearing loss. Cisplatin ototoxicity is associated with cochlear cell oxidative stress and mitochondrial damage. However, mitophagy is vital for maintaining mitochondrial quali...

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Detalles Bibliográficos
Autores principales:	Cho, Sung Il, Jo, Eu-Ri, Song, Hansoo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163551/ https://www.ncbi.nlm.nih.gov/pubmed/34095303 http://dx.doi.org/10.1155/2021/5590973

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