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An Update on Immune Checkpoint Therapy for the Treatment of Lynch Syndrome
During the recent years, immune checkpoint-based therapy has proven highly effective in microsatellite instable (MSI) solid tumors irrespective of organ site. MSI tumors are associated with a defective mismatch repair (MMR) system and a highly immune-infiltrative tumor microenvironment—both characte...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163581/ https://www.ncbi.nlm.nih.gov/pubmed/34079322 http://dx.doi.org/10.2147/CEG.S278054 |