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An Update on Immune Checkpoint Therapy for the Treatment of Lynch Syndrome

During the recent years, immune checkpoint-based therapy has proven highly effective in microsatellite instable (MSI) solid tumors irrespective of organ site. MSI tumors are associated with a defective mismatch repair (MMR) system and a highly immune-infiltrative tumor microenvironment—both characte...

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Detalles Bibliográficos
Autores principales: Therkildsen, Christina, Jensen, Lars Henrik, Rasmussen, Maria, Bernstein, Inge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163581/
https://www.ncbi.nlm.nih.gov/pubmed/34079322
http://dx.doi.org/10.2147/CEG.S278054