Cargando…
A preliminary metabolites identification of a novel compound with β-adrenolytic activity
BACKGROUND: The identification of main metabolites and assessment of renal excretion of a novel compound with β-adrenolytic activity (2RS)-1-(1H-indol-4-yloxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)propan-2-ol, briefly called (RS)-9 or 2F109, were studied in vivo in rat serum, urine, faeces, liver, in...
Autores principales: | Walczak, Maria, Suraj-Prażmowska, Joanna, Kuś, Kamil, Kij, Agnieszka, Groszek, Grażyna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163589/ https://www.ncbi.nlm.nih.gov/pubmed/34050907 http://dx.doi.org/10.1007/s43440-021-00273-9 |
Ejemplares similares
-
Synthesis and Adrenolytic Activity of New Propanolamines
por: Groszek, Grażyna, et al.
Publicado: (2010) -
Antiarrhythmic and antioxidant activity of novel pyrrolidin-2-one derivatives with adrenolytic properties
por: Sapa, Jacek, et al.
Publicado: (2010) -
Protein disulfide isomerase‐A1 regulates intraplatelet reactive oxygen species–thromboxane A(2)‐dependent pathway in human platelets
por: Przyborowski, Kamil, et al.
Publicado: (2021) -
HBK-10, A Compound with α(1)-Adrenolytic Properties, Showed Antiarrhythmic and Hypotensive Effects in Rats
por: Lustyk, Klaudia, et al.
Publicado: (2022) -
Direct Thrombin Inhibitor Dabigatran Compromises Pulmonary Endothelial Integrity in a Murine Model of Breast Cancer Metastasis to the Lungs; the Role of Platelets and Inflammation-Associated Haemostasis
por: Smeda, Marta, et al.
Publicado: (2022)