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c-Myc Upregulated by High Glucose Inhibits HaCaT Differentiation by S100A6 Transcriptional Activation

Keratinocyte differentiation dysfunction in diabetic skin is closely related to impaired skin barrier functions. We investigated the effects of c-Myc and S100A6 on Human immortal keratinocyte line (HaCaT) or keratinocyte differentiation and potential mechanisms. The expression levels of differentiat...

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Detalles Bibliográficos
Autores principales: Zhang, Jie, Yang, Peilang, Liu, Dan, Gao, Min, Wang, Jizhuang, Wang, Xiqiao, Liu, Yan, Zhang, Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163689/
https://www.ncbi.nlm.nih.gov/pubmed/34060533
http://dx.doi.org/10.3389/fendo.2021.676403