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SOX17 Antagonizes the WNT Signaling Pathway and is Epigenetically Inactivated in Clear-Cell Renal Cell Carcinoma

BACKGROUND: SRY-box containing gene 17 (SOX17) was reported to be a candidate tumor suppressor gene in multiple tumors. Little is known about its role in clear-cell renal cell carcinoma (ccRCC). This study aims to identify the epigenetic regulation and tumor-suppressive function of SOX17 in ccRCC. P...

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Detalles Bibliográficos
Autores principales:	Wang, Lu, Wang, Zhe, Zhu, Yuze, Tan, Shutao, Chen, Xiaonan, Yang, Xianghong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163727/ https://www.ncbi.nlm.nih.gov/pubmed/34079284 http://dx.doi.org/10.2147/OTT.S294164

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