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Remodeling of t-system and proteins underlying excitation-contraction coupling in aging versus failing human heart
It is well established that the aging heart progressively remodels towards a senescent phenotype, but alterations of cellular microstructure and their differences to chronic heart failure (HF) associated remodeling remain ill-defined. Here, we show that the transverse tubular system (t-system) and p...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163749/ https://www.ncbi.nlm.nih.gov/pubmed/34050186 http://dx.doi.org/10.1038/s41514-021-00066-7 |