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Remodeling of t-system and proteins underlying excitation-contraction coupling in aging versus failing human heart
It is well established that the aging heart progressively remodels towards a senescent phenotype, but alterations of cellular microstructure and their differences to chronic heart failure (HF) associated remodeling remain ill-defined. Here, we show that the transverse tubular system (t-system) and p...
Autores principales: | Lyu, Yankun, Verma, Vipin K., Lee, Younjee, Taleb, Iosif, Badolia, Rachit, Shankar, Thirupura S., Kyriakopoulos, Christos P., Selzman, Craig H., Caine, William, Alharethi, Rami, Navankasattusas, Sutip, Seidel, Thomas, Drakos, Stavros G., Sachse, Frank B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163749/ https://www.ncbi.nlm.nih.gov/pubmed/34050186 http://dx.doi.org/10.1038/s41514-021-00066-7 |
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