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Remodeling of t-system and proteins underlying excitation-contraction coupling in aging versus failing human heart

It is well established that the aging heart progressively remodels towards a senescent phenotype, but alterations of cellular microstructure and their differences to chronic heart failure (HF) associated remodeling remain ill-defined. Here, we show that the transverse tubular system (t-system) and p...

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Detalles Bibliográficos
Autores principales: Lyu, Yankun, Verma, Vipin K., Lee, Younjee, Taleb, Iosif, Badolia, Rachit, Shankar, Thirupura S., Kyriakopoulos, Christos P., Selzman, Craig H., Caine, William, Alharethi, Rami, Navankasattusas, Sutip, Seidel, Thomas, Drakos, Stavros G., Sachse, Frank B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163749/
https://www.ncbi.nlm.nih.gov/pubmed/34050186
http://dx.doi.org/10.1038/s41514-021-00066-7

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