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Pronounced proliferation of non-beta cells in response to beta-cell mitogens in isolated human islets of Langerhans
The potential to treat diabetes by increasing beta-cell mass is driving a major effort to identify beta-cell mitogens. Demonstration of mitogen activity in human beta cells is frequently performed in ex vivo assays. However, reported disparities in the efficacy of beta-cell mitogens led us to invest...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163757/ https://www.ncbi.nlm.nih.gov/pubmed/34050242 http://dx.doi.org/10.1038/s41598-021-90643-3 |