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Notch-Wnt signal crosstalk regulates proliferation and differentiation of osteoprogenitor cells during intramembranous bone healing

Adult bone regeneration is orchestrated by the precise actions of osteoprogenitor cells (OPCs). However, the mechanisms by which OPC proliferation and differentiation are linked and thereby regulated are yet to be defined. Here, we present evidence that during intramembranous bone formation OPC prol...

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Detalles Bibliográficos
Autores principales: Lee, S., Remark, L. H., Josephson, A. M., Leclerc, K., Lopez, E. Muiños, Kirby, D. J., Mehta, Devan, Litwa, H. P., Wong, M. Z., Shin, S. Y., Leucht, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163848/
https://www.ncbi.nlm.nih.gov/pubmed/34050174
http://dx.doi.org/10.1038/s41536-021-00139-x