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Mycotic infrarenal aortic aneurysm due to mycobacterium after intravesical treatment for bladder cancer

Intravesical instillation of Bacillus Calmette-Guerin, a live-attenuated strain of Mycobacterium bovis, is a common adjuvant therapy for bladder cancer with a low incidence of serious adverse events. The case described herein illustrates a rare complication of intravesical Bacillus Calmette-Guerin i...

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Detalles Bibliográficos
Autores principales: Pham, Steve Thanh D., Lee, Ashton, Struminger, Janin S., Belkoff, Kenneth M., Mendoza, Bernardo, Berman, Scott S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163880/
https://www.ncbi.nlm.nih.gov/pubmed/34095641
http://dx.doi.org/10.1016/j.jvscit.2021.02.011
Descripción
Sumario:Intravesical instillation of Bacillus Calmette-Guerin, a live-attenuated strain of Mycobacterium bovis, is a common adjuvant therapy for bladder cancer with a low incidence of serious adverse events. The case described herein illustrates a rare complication of intravesical Bacillus Calmette-Guerin instillation that resulted from invasion of the mycobacterium into tissue outside of the bladder lining, also known as microbial dissemination, leading to infection of the aortic wall and development of a mycotic aneurysm, and highlights the therapeutic challenges presented by the aortic pathology in this clinical scenario.