Integrating genomics and metabolomics for scalable non-ribosomal peptide discovery

Non-Ribosomal Peptides (NRPs) represent a biomedically important class of natural products that include a multitude of antibiotics and other clinically used drugs. NRPs are not directly encoded in the genome but are instead produced by metabolic pathways encoded by biosynthetic gene clusters (BGCs)....

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Detalles Bibliográficos
Autores principales: Behsaz, Bahar, Bode, Edna, Gurevich, Alexey, Shi, Yan-Ni, Grundmann, Florian, Acharya, Deepa, Caraballo-Rodríguez, Andrés Mauricio, Bouslimani, Amina, Panitchpakdi, Morgan, Linck, Annabell, Guan, Changhui, Oh, Julia, Dorrestein, Pieter C., Bode, Helge B., Pevzner, Pavel A., Mohimani, Hosein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163882/
https://www.ncbi.nlm.nih.gov/pubmed/34050176
http://dx.doi.org/10.1038/s41467-021-23502-4

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