Cargando…

Rationally designed bacterial consortia to treat chronic immune-mediated colitis and restore intestinal homeostasis

Environmental factors, mucosal permeability and defective immunoregulation drive overactive immunity to a subset of resident intestinal bacteria that mediate multiple inflammatory conditions. GUT-103 and GUT-108, live biotherapeutic products rationally designed to complement missing or underrepresen...

Descripción completa

Detalles Bibliográficos
Autores principales:	van der Lelie, Daniel, Oka, Akihiko, Taghavi, Safiyh, Umeno, Junji, Fan, Ting-Jia, Merrell, Katherine E., Watson, Sarah D., Ouellette, Lisa, Liu, Bo, Awoniyi, Muyiwa, Lai, Yunjia, Chi, Liang, Lu, Kun, Henry, Christopher S., Sartor, R. Balfour
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163890/ https://www.ncbi.nlm.nih.gov/pubmed/34050144 http://dx.doi.org/10.1038/s41467-021-23460-x

Ejemplares similares

COVID-19 and the Gut Microbiome: More than a Gut Feeling
por: van der Lelie, Daniel, et al.
Publicado: (2020)

Complete Genome Sequence of Clostridium sp. Strain DL-VIII, a Novel Solventogenic Clostridium Species Isolated from Anaerobic Sludge
por: Taghavi, Safiyh, et al.
Publicado: (2013)

Strategies to Dissect Host-Microbial Immune Interactions That Determine Mucosal Homeostasis vs. Intestinal Inflammation in Gnotobiotic Mice
por: Rogala, Allison R., et al.
Publicado: (2020)

The microbiome as a source of new enterprises and job creation: Considering clinical faecal and synthetic microbiome transplants and therapeutic regulation
por: van der Lelie, Daniel, et al.
Publicado: (2017)

Complex Bacterial Consortia Reprogram the Colitogenic Activity of Enterococcus faecalis in a Gnotobiotic Mouse Model of Chronic, Immune-Mediated Colitis
por: Lengfelder, Isabella, et al.
Publicado: (2019)

Comparative genomics and functional analysis of niche-specific adaptation in Pseudomonas putida
por: Wu, Xiao, et al.
Publicado: (2011)

Superior mesenteric artery syndrome: Diagnosis and management
por: Oka, Akihiko, et al.
Publicado: (2023)

Bioprospecting metagenomes: glycosyl hydrolases for converting biomass
por: Li, Luen-Luen, et al.
Publicado: (2009)

The Potential of Microalgae–Bacteria Consortia to Restore Degraded Soils
por: Gonzalez-Gonzalez, Lina M., et al.
Publicado: (2023)

The Emulsifier Carboxymethylcellulose Induces More Aggressive Colitis in Humanized Mice with Inflammatory Bowel Disease Microbiota Than Polysorbate-80
por: Rousta, Esmat, et al.
Publicado: (2021)

Genome Sequence of the Plant Growth Promoting Endophytic Bacterium Enterobacter sp. 638
por: Taghavi, Safiyh, et al.
Publicado: (2010)

Genome Sequence of Serratia plymuthica RVH1, Isolated from a Raw Vegetable-Processing Line
por: Van Houdt, Rob, et al.
Publicado: (2014)

Transcriptional Responses to Sucrose Mimic the Plant-Associated Life Style of the Plant Growth Promoting Endophyte Enterobacter sp. 638
por: Taghavi, Safiyh, et al.
Publicado: (2015)

Rationally-defined microbial consortia suppress multidrug-resistant proinflammatory Enterobacteriaceae via ecological control
por: Honda, Kenya, et al.
Publicado: (2023)

Probiotic Consortia and Their Metabolites Ameliorate the Symptoms of Inflammatory Bowel Diseases in a Colitis Mouse Model
por: Xu, Limin, et al.
Publicado: (2022)

2067. Preclinical Characterization of Rationally Designed Microbial Consortia to Prevent Bacterial Infections in Patients with Chronic Liver Disease
por: Halvorsen, Elizabeth, et al.
Publicado: (2023)

Protective and aggressive bacterial subsets and metabolites modify hepatobiliary inflammation and fibrosis in a murine model of PSC
por: Awoniyi, Muyiwa, et al.
Publicado: (2023)

Resident Bacteria-Stimulated Interleukin-10-Secreting B Cells Ameliorate T-Cell-Mediated Colitis by Inducing T-Regulatory-1 Cells That Require Interleukin-27 Signaling
por: Mishima, Yoshiyuki, et al.
Publicado: (2015)

Microbial consortia at steady supply
por: Taillefumier, Thibaud, et al.
Publicado: (2017)

Microscopic colitis: Etiopathology, diagnosis, and rational management
por: Nielsen, Ole Haagen, et al.
Publicado: (2022)

RICOPILI: Rapid Imputation for COnsortias PIpeLIne
por: Lam, Max, et al.
Publicado: (2019)

The Metagenome of an Anaerobic Microbial Community Decomposing Poplar Wood Chips
por: van der Lelie, Daniel, et al.
Publicado: (2012)

The Soil Microbiome Influences Grapevine-Associated Microbiota
por: Zarraonaindia, Iratxe, et al.
Publicado: (2015)

Phytoplankton consortia as a blueprint for mutually beneficial eukaryote-bacteria ecosystems based on the biocoenosis of Botryococcus consortia
por: Blifernez-Klassen, Olga, et al.
Publicado: (2021)

Homeostatic Regulation of Salmonella-Induced Mucosal Inflammation and Injury by IL-23
por: Awoniyi, Muyiwa, et al.
Publicado: (2012)

Dietary iron variably modulates assembly of the intestinal microbiota in colitis-resistant and colitis-susceptible mice
por: Ellermann, Melissa, et al.
Publicado: (2019)

The Cao-Xiang-Wei-Kang formula attenuates the progression of experimental colitis by restoring the homeostasis of the microbiome and suppressing inflammation
por: Yu, Wei, et al.
Publicado: (2022)

Dual functions of Rap1 are crucial for T-cell homeostasis and prevention of spontaneous colitis
por: Ishihara, Sayaka, et al.
Publicado: (2015)

Phosphoinositide 3-Kinase P110δ-Signaling Is Critical for Microbiota-Activated IL-10 Production by B Cells that Regulate Intestinal Inflammation
por: Oka, Akihiko, et al.
Publicado: (2019)

Navigating the Patent Minefield Through Consortia
por: Lopez-Berzosa, David
Publicado: (2016)

International Coalition of Library Consortia 2007
Publicado: (2007)

Engineering microbial consortia for controllable outputs
por: Lindemann, Stephen R, et al.
Publicado: (2016)

Engineering microbial consortia by division of labor
por: Roell, Garrett W., et al.
Publicado: (2019)

Majority sensing in synthetic microbial consortia
por: Alnahhas, Razan N., et al.
Publicado: (2020)

Single strain control of microbial consortia
por: Fedorec, Alex J. H., et al.
Publicado: (2021)

An era of single-cell genomics consortia
por: Ando, Yoshinari, et al.
Publicado: (2020)

Engineered microbial consortia: strategies and applications
por: Duncker, Katherine E., et al.
Publicado: (2021)

Engineering consortia by polymeric microbial swarmbots
por: Wang, Lin, et al.
Publicado: (2022)

Artificial microbial consortia for bioproduction processes
por: Mittermeier, Fabian, et al.
Publicado: (2022)

Dietary Fructose Alters the Composition, Localization, and Metabolism of Gut Microbiota in Association With Worsening Colitis
por: Montrose, David C., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ptobhvol9qlar3libu813af519