A comprehensive analysis of RAS-effector interactions reveals interaction hotspots and new binding partners

RAS effectors specifically interact with GTP-bound RAS proteins to link extracellular signals to downstream signaling pathways. These interactions rely on two types of domains, called RAS-binding (RB) and RAS association (RA) domains, which share common structural characteristics. Although the molec...

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Detalles Bibliográficos
Autores principales: Rezaei Adariani, Soheila, Kazemein Jasemi, Neda S., Bazgir, Farhad, Wittich, Christoph, Amin, Ehsan, Seidel, Claus A.M., Dvorsky, Radovan, Ahmadian, Mohammad R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163975/
https://www.ncbi.nlm.nih.gov/pubmed/33930461
http://dx.doi.org/10.1016/j.jbc.2021.100626

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